ABSTRACT
Pharmacological management of pain for acute and chronic conditions has been guided by a scientific understanding of peripheral and central acting mechanisms for the control of inflammation as well as pain. Oral surgery pain is a reliable model to reference the effectiveness of commonly used analgesics such as ibuprofen and acetaminophen. A total of 706 patients who were experiencing moderate to severe pain received a single dose of ibuprofen, acetaminophen, or placebo. After 6 hours, the degree of pain relief and tolerance was assessed. Ibuprofen has important implications for postoperative pain in clinical practice.
Subject(s)
Acetaminophen/therapeutic use , Ibuprofen/therapeutic use , Pain, Postoperative/drug therapy , Acetaminophen/adverse effects , Adolescent , Adult , Double-Blind Method , Female , Humans , Ibuprofen/adverse effects , Male , Middle Aged , Mouth/surgery , Multicenter Studies as Topic , Pain Measurement , Placebos , Randomized Controlled Trials as Topic , Time Factors , Tooth/surgeryABSTRACT
Hemophilic pseudotumor of bone is a rarely encountered lesion associated with hemophilia. To date, only eight cases in the mandible have been reported in the literature. A rare case occurring in the mandible of a 2 1/2-year-old child required the fabrication of a customized wound obturator for postoperative wound care after surgical curettage. The literature is reviewed and the obturator described.
Subject(s)
Hematoma/complications , Hemophilia A/complications , Jaw Cysts/surgery , Mandibular Diseases/surgery , Child, Preschool , Humans , Jaw Cysts/etiology , Male , Mandibular Diseases/etiology , Prostheses and Implants , Prosthesis DesignABSTRACT
In a multicenter study, 77 edentulous patients had mandibular augmentation with implants of purified fibrillar collagen combined with dense hydroxylapatite (Alveoform Biograft); 22 of these patients also had maxillary augmentation. Most patients had Class III or IV mandibular atrophy, and had outpatient surgery with the subperiosteal tunneling technique. Temporary splints were worn for 24 hours post-surgery. Mean ridge height was 15.3 mm before surgery and 19.5 mm after 12 months, an augmentation of 4.2 mm. Predictable compaction occurred largely in the first few months after denture loading. Most patients, surgeons, and prosthodontists assessed the results of the procedure as good to excellent at 1 year following implantation. Adverse experiences, largely dehiscence and paresthesia, tended to resolve over time. Sera from ten patients demonstrated antibodies to bovine collagen that were not clinically significant. Alveolar augmentation with collagen/hydroxylapatite achieved clinically significant results that compared favorably with those achieved with other types of ceramic implants.
Subject(s)
Alveolar Ridge Augmentation/methods , Collagen , Hydroxyapatites , Mouth, Edentulous/surgery , Oral Surgical Procedures, Preprosthetic/methods , Prostheses and Implants , Adult , Aged , Aged, 80 and over , Durapatite , Female , Humans , Male , Middle Aged , Multicenter Studies as TopicABSTRACT
A multicenter study was undertaken to evaluate a new alveolar ridge augmentation material composed of purified fibrillar collagen and particulate hydroxylapatite (PFC/HA). In a study of 77 patients and 99 reconstructed ridges, this material provided superior handling properties over HA alone as evidenced by its ease of surgical placement and manipulation, and the rarity of particle migration or displacement. Moreover, the rapid development of ridge firmness and stability allowed for the loading of dentures within three to six weeks. Prosthodontist evaluations and surveys of patient satisfaction showed great satisfaction with denture fit, comfort, esthetics, speech, and ability to masticate.
