1.
Br Med J
; 4(5731): 342-4, 1970 Nov 07.
Article
in English
| MEDLINE
| ID: mdl-4394369
ABSTRACT
In controlled trials of the beta-adrenergic blocking drugs oxprenolol and practolol in hypertension both drugs were well tolerated without side effects and caused statistically significant non-postural reduction of blood pressure. In less than half the patients on eitherdrug the reduction of blood pressure was clinically adequate. No attempt was made to compare the two drugs.
Subject(s)
Acetanilides/therapeutic use , Amino Alcohols/therapeutic use , Hypertension/drug therapy , Propylamines/therapeutic use , Sympathomimetics/therapeutic use , Adrenergic beta-Antagonists/therapeutic use , Blood Pressure , Clinical Trials as Topic , Humans , Posture
2.
Clin Pharmacol Ther
; 11(3): 423-31, 1970.
Article
in English
| MEDLINE
| ID: mdl-5445743
Subject(s)
Guanethidine/metabolism , Hypertension/metabolism , Administration, Oral , Aged , Animals , Chromatography , Feces/analysis , Glomerular Filtration Rate , Guanethidine/administration & dosage , Guanethidine/blood , Guanethidine/therapeutic use , Guanethidine/urine , Humans , Hypertension/drug therapy , Injections, Intramuscular , Liver/metabolism , Middle Aged , Time Factors , Tritium
3.
Circulation
; 38(3): 542-51, 1968 Sep.
Article
in English
| MEDLINE
| ID: mdl-4876981
Subject(s)
Guanethidine/therapeutic use , Hypertension/drug therapy , Phenoxybenzamine/pharmacology , Clinical Trials as Topic , Drug Synergism , Heart Rate/drug effects , Humans , Injections, Intravenous , Norepinephrine/pharmacology , Placebos , Sympathetic Nervous System/drug effects , Valsalva Maneuver
4.
Br Med J
; 1(5584): 120, 1968 Jan 13.
Article
in English
| MEDLINE
| ID: mdl-5634708
5.
Angiology
; 18(11): 705-16, 1967 Nov.
Article
in English
| MEDLINE
| ID: mdl-6073008
Subject(s)
Guanethidine/therapeutic use , Hypertension/drug therapy , Albuminuria/drug therapy , Angina Pectoris/drug therapy , Blood Pressure , Cerebrovascular Disorders/drug therapy , Female , Follow-Up Studies , Guanethidine/adverse effects , Heart Failure/drug therapy , Humans , Hypertension/mortality , Kidney Function Tests , Male , Urea/blood
6.
Practitioner
; 196(171): 127, 1966 Jan.
Article
in English
| MEDLINE
| ID: mdl-5902438
