ABSTRACT
Se presenta el caso clínico de una paciente que ingresó en nuestro servicio por clínica de poliartralgias, fiebre y lesiones cutáneas que afectaban a la región glútea y pretibial. Refería como antecedente la aplicación de inyecciones de silicona líquida en los glúteos con fines estéticos 3 años antes. Se realizó una biopsia cutánea de las lesiones en la región glútea, cuyo estudio anatomopatológico fue compatible con paniculitis facticia por silicona, así como de la región pretibial, que fueron compatibles con eritema nudoso. La radiografía de tórax y la tomografía torácica mostraron adenopatías hiliares bilaterales y en la biopsia transbronquial se evidenció un componente inflamatorio granulomatoso. La evolución fue satisfactoria con reposo y antiinflamatorios no esteroideos, por lo que no fue necesaria la extracción de la silicona (AU)
We herein report a patient who came to the hospital because of a polyarticular joint pain, fever and cutaneous lesions. She had silicone implants in her buttocks, a surgery performed 3 years before. We made a biopsy of the skin of the buttocks (facticial panniculitis due to silicone) and of the pretibial surface of the inferior extremities (erythema nodosum). A chest X- ray and a CT scan revealed bilateral hiliar lymphadenopathy, and a transbronquial biopsy showed granulomatous inflammation. She had a good response to rest and anti-inflammatory drugs, so the removal of the silicone implants has not been necessary yet (AU)
Subject(s)
Humans , Female , Adult , Panniculitis/complications , Panniculitis/diagnosis , Silicone Elastomers/adverse effects , Silicone Gels/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Erythema Nodosum/complications , Erythema Nodosum/diagnosis , Panniculitis/physiopathology , Panniculitis , Erythema/complications , Erythema/diagnosis , Erythema/drug therapyABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Sjogren's Syndrome/physiopathology , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/physiopathology , Risk Factors , Mononeuropathies/complicationsSubject(s)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/etiology , Sjogren's Syndrome/complications , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/epidemiology , Antibodies, Antineutrophil Cytoplasmic/blood , Antibodies, Antinuclear/blood , Autoantigens/immunology , Comorbidity , Humans , Kidney/blood supply , Kidney/pathology , Kidney Failure, Chronic/etiology , Male , Middle Aged , Peroxidase/immunology , Polyarteritis Nodosa/etiology , Polyarteritis Nodosa/pathology , Prevalence , Sjogren's Syndrome/epidemiology , Sjogren's Syndrome/immunologyABSTRACT
We herein report a patient who came to the hospital because of a polyarticular joint pain, fever and cutaneous lesions. She had silicone implants in her buttocks, a surgery performed 3 years before. We made a biopsy of the skin of the buttocks (facticial panniculitis due to silicone) and of the pretibial surface of the inferior extremities (erythema nodosum). A chest X- ray and a CT scan revealed bilateral hiliar lymphadenopathy, and a transbronquial biopsy showed granulomatous inflammation. She had a good response to rest and anti-inflammatory drugs, so the removal of the silicone implants has not been necessary yet.
Subject(s)
Cosmetic Techniques/adverse effects , Erythema Nodosum/diagnosis , Panniculitis/diagnosis , Prostheses and Implants/adverse effects , Sarcoidosis/diagnosis , Silicones/adverse effects , Adult , Erythema Nodosum/etiology , Female , Humans , Panniculitis/etiology , Sarcoidosis/etiology , SyndromeABSTRACT
La artritis psoriásica con afección periférica es una enfermedad inflamatoria progresiva, cuyo impacto, tanto a nivel de daño estructural como en la función y calidad de vida de los pacientes, es similar a otras poliartritis crónicas. A pesar del tratamiento con FAME sintéticos o biológicos, la remisión solo se alcanza en un 30% de los pacientes. Desde el punto de vista clínico, la actividad articular mantenida (dolor e hinchazón) es un factor de progresión del daño articular, por ello existe la necesidad de un seguimiento y tratamiento estrecho de estos pacientes (AU)
Peripheral psoriatic arthritis is an inflammatory and progressive disease; its burden, either at the structural level or the function and quality of life, is similar to other chronic poliarthritidies. In spite of treatment with synthetic or biologic DMARDs, remission is only achieved in about 30% of the patients. From a clinical point of view, persistent joint activity (tender and swollen joints) is a factor leading to joint damage progression. These data indicate the need for a tight follow up and treatment of the patients (AU)
Subject(s)
Humans , Arthritis, Psoriatic/drug therapy , Arthritis, Psoriatic/epidemiology , Arthritis, Psoriatic/pathology , Prognosis , Antirheumatic Agents , Acute-Phase Proteins/analysis , Adrenal Cortex Hormones/therapeutic use , Cross-Sectional Studies , Disease Progression , Drug Therapy, Combination , Joints/pathology , Quality of Life , Remission InductionABSTRACT
Peripheral psoriatic arthritis is an inflammatory and progressive disease; its burden, either at the structural level or the function and quality of life, is similar to other chronic poliarthritidies. In spite of treatment with synthetic or biologic DMARDs, remission is only achieved in about 30% of the patients. From a clinical point of view, persistent joint activity (tender and swollen joints) is a factor leading to joint damage progression. These data indicate the need for a tight follow up and treatment of the patients.
