ABSTRACT
Ocular rosacea was diagnosed in 6.3% of a cornea/external disease referral practice where more than half of the patients referred are for corneal surgery. The most common signs and symptoms are also common to many patients in the general practice of ophthalmology, i.e., foreign body sensation, burning, superficial punctate erosions, chalazia and blepharitis. Less common but dangerous to the vision was corneal thinning, vascularization and infiltrates. Three new associated symptoms were described. These were map dot subepithelial opacities, recurrent erosions and moderately severe foreign body sensation, pain or burning with minimal associated signs. Oral tetracycline 250 mg q.i.d. resulted in improvement in almost all patients from 4 to 17 days after initiation of therapy. Although most of the patients have been able to taper and stop therapy, those with foreign body sensation, burning and pain have had recurrences of their symptoms with all attempts at stopping therapy.
Subject(s)
Conjunctival Diseases/diagnosis , Corneal Diseases/diagnosis , Eyelid Diseases/diagnosis , Rosacea/diagnosis , Tetracycline/administration & dosage , Adult , Aged , Conjunctival Diseases/drug therapy , Conjunctival Diseases/pathology , Corneal Diseases/drug therapy , Corneal Diseases/pathology , Eyelid Diseases/drug therapy , Eyelid Diseases/pathology , Female , Humans , Male , Middle Aged , Rosacea/drug therapy , Rosacea/pathology , Time FactorsSubject(s)
Cataract Extraction/methods , Iris/surgery , Lenses, Intraocular/methods , Adult , Aged , Corneal Diseases/complications , Equipment Failure , Female , Glaucoma/complications , Humans , Iris Diseases/complications , Lenses, Intraocular/standards , Male , Middle Aged , Postoperative Complications , Retinal Detachment/complications , Uveitis/complicationsSubject(s)
Cicatrix/diagnosis , Cornea/surgery , Light , Myopia/surgery , Humans , Male , Postoperative Complications/diagnosisABSTRACT
Ocular rosacea was diagnosed in 49 patients. The most common signs and symptoms were foreign body sensation, burning, superficial punctate erosions, chalazia, and belpharitis. Less common but dangerous to the vision was corneal thinning, vascularization, and infiltrates. Three new associated symptoms were found. These were mapdot subepithelial opacities, recurrent erosions, and moderately severe foreign body sensation, pain or burning with minimal associated signs. Of the 49 patients, 37 were treated with 250 mg of oral tetracycline four times a day, which resulted in improvement in almost all patients from four to 17 days after initiation of therapy. Most of the patients have been able to taper, or taper and stop therapy without recurrence of their symptoms. Those patients with foreign body sensation, burning, and pain required the most prolonged therapy in order to taper or stop treatment with tetracycline.
Subject(s)
Eye Diseases/diagnosis , Rosacea/diagnosis , Adolescent , Adult , Aged , Eye Diseases/drug therapy , Female , Humans , Male , Middle Aged , Rosacea/drug therapy , Tetracycline/therapeutic useABSTRACT
Fifty-seven percent of patients scheduled for excision of chalazia over 19 years of age and 64% of patients over the age of 29 were found to have rosacea. This compares to an incidence in our control group of 12% and 13%, respectively. Rosacea was almost twice as common in patients with recurrent chalazia as in those with only one occurrence.
Subject(s)
Cysts/complications , Eyelid Diseases/complications , Rosacea/complications , Adult , Aged , Cysts/surgery , Eyelid Diseases/surgery , Female , Humans , Male , Meibomian Glands , Middle Aged , Recurrence , Rosacea/diagnosisABSTRACT
Because the significance of donor age in penetrating keratoplasty remains controversial, a study was undertaken to analyze the results of keratoplastics performed with older (greater than 70) and younger (less than 55) donor corneas. Thirty-seven eyes which received older donor corneas were divided into 4 diagnostic categories and were compared with 37 eyes having the same diagnosis which received younger donor corneas. The average follow-up for both groups was 24 months. There was no significant difference between the number of clear grafts in each group. It would appear that older donor corneas can withstand the surgical trauma of transplantation and remain clear for a relatively significant period.
Subject(s)
Corneal Transplantation , Graft Survival , Tissue Donors , Age Factors , Aged , Aphakia/complications , Corneal Diseases/surgery , Corneal Dystrophies, Hereditary/surgery , Humans , Keratoconus/surgery , Middle Aged , Prognosis , Transplantation, HomologousABSTRACT
Controlled aspiration of aqueous before excising the recipient cornea resulted in maintenance of an intact vitreous face during aphakic penetrating corneal transplants in eight of 11 eyes. Vitreous corneal contact or subsequent graft opacification has not occurred in the study group during the observation period.
Subject(s)
Anterior Chamber/surgery , Aphakia, Postcataract/complications , Corneal Transplantation , Vitreous Body , Graft Survival , Humans , Transplantation, HomologousABSTRACT
A 63-year-old man and his 24-year-old son developed recurrences of granular dystrophy in their three corneal grafts within three years after surgery. We regrafted one of the son's corneas. Histologic examination of the corneal button removed during surgery showed an avascular connective tissue layer with the histochemical characteristics of granular dystrophy interposed between the epithelium and Bowman's layer. In the remaining two corneal grafts, we fixed the globe with corneal forceps and removed the opaque dystrophic layer by separating it from the cornea with a spatula. Postoperatively, all three corneal grafts were once more transparent.