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Neurology ; 49(2): 593-5, 1997 Aug.
Article in English | MEDLINE | ID: mdl-9270603

ABSTRACT

The 14-3-3 protein, a protein involved in signal transduction, is present in the CSF of patients with Creutzfeldt-Jakob disease (CJD) and not in patients with other dementing diseases. We show here that this is also true for patients with E200K CJD, but not for healthy carriers of the mutation.


Subject(s)
Creutzfeldt-Jakob Syndrome/cerebrospinal fluid , Proteins/analysis , Tyrosine 3-Monooxygenase , 14-3-3 Proteins , Carrier State/cerebrospinal fluid , Creutzfeldt-Jakob Syndrome/genetics , Humans , Immunoassay , Mutation , Nervous System Diseases/cerebrospinal fluid , Nervous System Diseases/genetics
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