ABSTRACT
Ursodeoxycholic acid, 10 to 20 mg/kg per day, was administered for 1 year to 22 patients with cystic fibrosis and chronic cholestasis, resulting in significantly improved liver enzyme values. However, evidence of cholestasis continued, as shown by the pattern of alkaline phosphatase isoenzymes.
Subject(s)
Cholestasis/drug therapy , Cystic Fibrosis/drug therapy , Liver/drug effects , Ursodeoxycholic Acid/therapeutic use , 5'-Nucleotidase/analysis , Adolescent , Adult , Alanine Transaminase/analysis , Alkaline Phosphatase/analysis , Aspartate Aminotransferases/analysis , Bile Acids and Salts/analysis , Bilirubin/analysis , Child , Cholestasis/enzymology , Chronic Disease , Cystic Fibrosis/enzymology , Female , Humans , Liver/enzymology , Male , gamma-Glutamyltransferase/analysisSubject(s)
Thyroidectomy/adverse effects , Vocal Cord Paralysis/etiology , Aged , Female , Humans , Laryngoscopy , Tracheotomy , Vocal Cord Paralysis/therapyABSTRACT
Electrical stimulation of the middle ear can provoke sound sensations in 90 p. cent of patients with total deafness, as shown by auditory evoked potentials brain stem recordings. This signifies that cochlear nerve destruction is not complete, and rehabilitation by multiple electrode cochlear implants is possible. The liminal stimulation threshold level appears to be inversely proportional to the functional quality of the electrode-nerve interface obtained by the implants. The electrical stimulation of the middle ear test is therefore essential for selection of patients for operation, and for predicting the quality of rehabilitation that will be obtained.
