ABSTRACT
OBJECTIVE: To increase reliability of the algorithm used in our fully automated electronic surveillance system by adding rules to better identify bloodstream infections secondary to other hospital-acquired infections. METHODS: Intensive care unit (ICU) patients with positive blood cultures were reviewed. Central line-associated bloodstream infection (CLABSI) determinations were based on 2 sources: routine surveillance by infection preventionists, and fully automated surveillance. Discrepancies between the 2 sources were evaluated to determine root causes. Secondary infection sites were identified in most discrepant cases. New rules to identify secondary sites were added to the algorithm and applied to this ICU population and a non-ICU population. Sensitivity, specificity, predictive values, and kappa were calculated for the new models. RESULTS: Of 643 positive ICU blood cultures reviewed, 68 (10.6%) were identified as central line-associated bloodstream infections by fully automated electronic surveillance, whereas 38 (5.9%) were confirmed by routine surveillance. New rules were tested to identify organisms as central line-associated bloodstream infections if they did not meet one, or a combination of, the following: (I) matching organisms (by genus and species) cultured from any other site; (II) any organisms cultured from sterile site; (III) any organisms cultured from skin/wound; (IV) any organisms cultured from respiratory tract. The best-fit model included new rules I and II when applied to positive blood cultures in an ICU population. However, they didn't improve performance of the algorithm when applied to positive blood cultures in a non-ICU population. CONCLUSION: Electronic surveillance system algorithms may need adjustment for specific populations.
Subject(s)
Catheter-Related Infections/prevention & control , Cross Infection , Infection Control/methods , Medical Informatics Applications , Sentinel Surveillance , Sepsis/diagnosis , Algorithms , Bacteremia/diagnosis , Bacteremia/prevention & control , Catheterization, Central Venous/adverse effects , Cross Infection/blood , Cross Infection/diagnosis , Cross Infection/microbiology , Cross Infection/prevention & control , Databases, Factual , Hospitals , Humans , Illinois , Intensive Care Units , Missouri , Reproducibility of Results , Sepsis/microbiology , Sepsis/prevention & controlABSTRACT
This practice forum report details a standardized improvement process that was created both to improve patient outcomes related to various hospital-acquired infections and to address leadership concerns related to incented quality metrics. A 3-year retrospective review identified common issues to guide future interventions and confirmed that this methodology reduced the rate of recurrent infections across the health care system. Process tool samples are provided.
