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1.
J Vasc Surg ; 58(3): 814-26, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23972249

ABSTRACT

Vascular surgery has seen a revolutionary transformation in its approach to peripheral vascular disease over the last 2 decades, fueled by technological innovation and a willingness by the field to adopt these changes. However, the underlying pathology behind critical limb ischemia and the significant rate of unhealed wounds and secondary amputations despite apparently successful revascularization needs to be addressed. In seeking to improve outcomes, it may be beneficial to examine our approach to vascular disease at the fundamental level of anatomy, the angiosome, to better dictate reperfusion strategies beyond a simple determination of open vs endovascular procedure. We performed a systematic review of the current literature concerning the significance of the angiosome concept in the realm of vascular surgery. The dearth of convincing evidence in the form of prospective trials and large patient populations, and the lack of a consistent, comparable vocabulary to contrast study findings, prevent recommendation of the conceptual model at a wider level for guidance of revascularization attempts. Further well-structured, prospective studies are required as well as emerging imaging strategies, such as indocyanine green dye-based fluorescent angiography or hyperspectral imaging, to allow wider adoption of the angiosome model in vascular operations.


Subject(s)
Extremities/blood supply , Models, Cardiovascular , Peripheral Vascular Diseases/surgery , Vascular Surgical Procedures , Collateral Circulation , Diagnostic Imaging/methods , Hemodynamics , Humans , Peripheral Vascular Diseases/diagnosis , Peripheral Vascular Diseases/physiopathology , Predictive Value of Tests , Regional Blood Flow , Treatment Outcome
2.
J Vasc Surg ; 56(2): 545-54, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22840905

ABSTRACT

The uncertainty continues over the best approach to patients with symptomatic peripheral arterial disease. Medical therapy and risk factor modification is part of any treatment regimen; with this there is little disagreement. However, with the introduction of lesser invasive percutaneous technologies, the discussion regarding surgical and endovascular therapies has become more and more complicated. Unfortunately, there is a relative shortage of robust outcomes data to support many of our specific treatment recommendations. Younger patients are an especially troublesome patient cohort. They have consistently shown poorer outcomes after any intervention compared with older patients and may represent a subset of more aggressive atherosclerotic disease. Our debaters will discuss their preferred approaches to these difficult patients in the context of the currently available supporting literature.


Subject(s)
Ischemia/surgery , Leg/blood supply , Peripheral Arterial Disease/surgery , Vascular Surgical Procedures/methods , Age Factors , Angioplasty , Endovascular Procedures , Humans , Inguinal Canal/blood supply , Inguinal Canal/surgery , Intermittent Claudication/surgery , Limb Salvage , Middle Aged , Randomized Controlled Trials as Topic , Vascular Patency
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