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Bioorg Med Chem Lett
; 19(2): 410-4, 2009 Jan 15.
Article
in English
| MEDLINE
| ID: mdl-19070486
ABSTRACT
Isoquinoline-based non-nucleoside inhibitors of HCV NS5b RNA-dependent RNA-polymerase are described. The synthesis and structure-activity relationships are detailed, along with enzyme and cellular activity.