ABSTRACT
The authors have examined a group of 30 patients at 24-36 months after extensive resections within the alimentary tract. The bone density assessment has been done. The results were compared to those obtained from another group of 30 patients awaiting sinister operations. Bone loss was found in all postoperative patients. However, it was statistically significant only in patients after pancreatoduodenectomy.
Subject(s)
Bone Density , Bone Diseases, Metabolic/etiology , Pancreaticoduodenectomy/adverse effects , Adult , Bone Diseases, Metabolic/diagnosis , Chi-Square Distribution , Digestive System Surgical Procedures/adverse effects , Follow-Up Studies , Humans , Middle Aged , Regression AnalysisABSTRACT
The aim of the study was to compare two types of anastomosis of the pancreatic stump with the digestive tract after pancreatoduodenectomy. 64 patients have been studied. Eighteen of them underwent pancreatoduodenectomy followed by the anastomosis of the pancreatic stump with the posterior wall of the stomach, in 46 patients pancreato-jejunal anastomosis has been done. Short term results of those two types of anastomosis did not differ significantly. Pancreato-gastric anastomosis seems to be technically easier, can be endoscopically controlled and does not impair recovery of gastric motility.
Subject(s)
Gastrectomy/methods , Jejunum/surgery , Pancreas/surgery , Pancreaticoduodenectomy/methods , Adult , Aged , Aged, 80 and over , Anastomosis, Surgical/methods , Chronic Disease , Endoscopy , Female , Humans , Male , Middle Aged , Pancreatic Diseases/surgeryABSTRACT
The aim of the study was to evaluate the value of duodenojejunostomy and gastrojejunostomy in the treatment of neoplastic obstruction in the distal part of the duodenum. From 1992-1996, 37 patients (15 women, 22 men, aged 31-76 years) underwent a palliative operation for pancreatic cancer infiltrating the distal part of duodenum. Roux-en-Y procedure was used to create anastomoses between the duodenal bulb and jejunal loop. In 13 patients only alimentary by-pass was made whereas in the remaining 24 biliary decompression was also performed. The results were compared with the outcome in 26 patients in whom gastrojejunal side-to-side anastomosis been made. The advantage of Roux-en-Y duodenojejunostomy is that it does not interfere with gastric emptying and thus prevents jejuno biliary reflux and the consequent complications. Improvement of nutrition and quality of life in patients with inoperable pancreatic cancer, were noticed with this method.
Subject(s)
Duodenal Diseases/surgery , Intestinal Obstruction/surgery , Jejunal Diseases/surgery , Pancreatic Neoplasms/complications , Adult , Aged , Aged, 80 and over , Anastomosis, Roux-en-Y , Duodenal Diseases/physiopathology , Duodenal Neoplasms/secondary , Duodenal Neoplasms/surgery , Duodenostomy/methods , Female , Gastric Emptying , Gastrostomy , Humans , Intestinal Obstruction/etiology , Intestinal Obstruction/physiopathology , Jejunal Diseases/physiopathology , Jejunostomy/methods , Male , Middle Aged , Palliative Care , Quality of LifeABSTRACT
Reinforcing properties of serotonin administration to the lateral hypothalamus were tested on the experimental model of the T-maze learning in 19 rats. The results did not definitely prove either positive or negative reinforcement produced by the central serotonergic stimulation, although the rats modified their behavior in the maze in the response to intrahypothalamic serotonin. It seems that the central serotonergic neurons do not play a decisive role in the mediation of the reinforcing phenomena but they may interact with the activity of some other reward neurons.
