ABSTRACT
Photodynamic therapy (PDT) was given to 61 patients with recurrent cancer of the tongue, oral mucosa, lower lip, oro- and nasopharynx, larynx. Photosensitizers photogem and photosens of Russian produce were employed. The radiation was given twice with the interval 24 and 48 hours, the exposure to light 3 to 30 min. The impact was external, through the instrumental canal of the fibroscope, by intracavitary and interstitial techniques. The response was assessed within 4-6 weeks after the PDT course. The effect was observed in 95.1% patients. Its duration ranged from 4 months to 5 years. Complete resorption of the tumor was achieved in 57.4%. The treatment failed in 4.9% patients.
Subject(s)
Carcinoma/therapy , Laryngeal Neoplasms/therapy , Nasopharyngeal Neoplasms/therapy , Oropharyngeal Neoplasms/therapy , Phototherapy/methods , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Neoplasm, Residual , Treatment OutcomeABSTRACT
The paper describes experimental and clinical results obtained with application of laser radiation (wave length 1.54 microm). The source of the radiation was a new surgical laser unit Glasser. The techniques and advantages of the above radiation treatment are characterized.