Evidence of objective sleep impairment in nonepileptic attack disorder: A naturalistic prospective controlled study using actigraphy and daily sleep diaries over six nights.

Poor sleep is reported by many with nonepileptic attack disorder (NEAD) with correlations evident between self-reported sleep quality and mood and functional impairment. However, it is contended that self-reported sleep impairment in NEAD is a subjective phenomenon, which represents a general tendency to over-report symptoms or misinterpret bodily states in those with NEAD. The present study was therefore designed to investigate the extent of subjective and objective sleep impairments in those with NEAD. Over six nights we prospectively recorded comparable nightly objective (actigraphy) and subjective (consensus sleep diary) sleep parameters in a sample of 17 people with NEAD, and an age- and gender-matched normative control group (N = 20). Participants recorded daily measures of attacks, dissociation, and mood. Alongside higher subjective sleep impairment, the NEAD group had significantly worse objective sleep on several metrics compared to the normative controls, characterized by disrupted sleep (frequent awakenings and wake after sleep onset, low efficiency). Exploratory analyses using mixed effects models showed that attacks were more likely to occur on days preceded by longer, more restful sleep. This study, which had good ecological validity, evidences the presence of objective sleep impairment in NEAD, suggesting that in patient reports of problems with sleep should be given careful consideration in clinical practice.

Assessment of an urgency classification for assisted vaginal delivery.

We performed a prospective observational audit to evaluate the application of the Lucas caesarean section urgency classification to assisted vaginal delivery in the operating theatre. We collected data from 400 women having category 1-3 delivery in the operating theatre. Twenty percent of the caesarean sections and 4% of the vaginal deliveries were category 1. The median (IQR) decision-delivery interval was 25 (19.5-37) min for category 1 caesarean section and 19.5 (15-29) min for category 1 vaginal delivery, and 43.5 (36-57) min and 45 (32-57) for category 2 caesarean section and vaginal delivery, respectively. Sixty-three percent of category 1 caesarean section and 75% of category 1 vaginal delivery were performed in ≤30 min. Antenatal or intrapartum risk factors were present before the decision for delivery in 82% of caesarean sections and 80% of vaginal deliveries. The application of the Lucas urgency classification to assisted vaginal delivery merits further evaluation.

Is uniport thoracoscopic surgery less painful than multiple port approaches?

A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was 'In patients undergoing Video-Assisted Thoracoscopic Surgery (VATS), does a uniport (single-port) or multiport technique convey benefit in terms of postoperative pain?' Altogether, 255 papers were found using the reported search, of which 12 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studies, study type, relevant outcomes and results of these tables are tabulated. All the available evidence is from small, non-randomized studies. Many were retrospective and methodologically weak. Most studied minor thoracic surgical procedures and a few compare the two approaches in major pulmonary resections. One of the studies compared pain at 24 h for uniport [mean Visual Analogue Scale (VAS) >4.4] and three-port VATS (mean VAS 6.2), for different procedures including lung biopsy and surgery for pneumothorax (P = 0.035). Another study compared pain in the first 36-h post-sympathectomy and found mean pain scores of 0.8 in the uniport group and 1.2 in the two-port group (P = 0.025). Six studies exclusively compared the VAS between uniport and three-port VATS for primary spontaneous pneumothorax. Two studies found no significant difference in pain scores and four found a statistically significant reduction in early postoperative pain scores. One study found that pain scores were similar for lung volume reduction surgery. Two studies compared the mean VAS and morphine use between uniportal and multiportal lobectomies; however, there were no statistically significant differences. From the papers identified in our search, we conclude that uniport VATS may have a small clinical effect in reducing postoperative pain, with the majority of papers looking at the first 72 h following surgery. Often the VAS score was only improved in the uniport patients by 1-2 points, and the studies did not find statistically significant results throughout their investigations, especially when looking at follow-up pain scores. Around one-third of the chosen papers did not find any statistically significant results. Further studies are needed before single-port can be recommended as less painful than multiport thoracoscopic surgery.