[Influence of hyperbaric stress on metabolic reactions of the organism of divers, prevention].

Research of metabolic rates is conducted in a blood of the subjects whose professional work is connected with the systematic implementation of diving on the large and medium depths. For restoration of working capacity and preservation of health of divers was carried pharmacological prophylaxis with supplementation "Kalifen", which is the total polyphenol complex isolated from viburnum (Viburnum sargentii Koehne). The blood plasma of divers, investigated after a dive, there was hypertriglyceridemia and hypercholesterolemia, the suppression of esterified liver function, an imbalance of fractional content of phospholipids, the strain of antioxidant defense of an organism and increased lipid peroxidation. Preventive administration supplementation "Kalifen" for 2 months before the dive will help remove metabolic disorders caused by hyperbaric factors, and also to store up of anabolic reserves and increase body resistance level in extreme conditions.

[Application of food supplement, of a duilder-rose for prevention of stressful disturbance of physiological and biochemical characteristics of erythrocytes].

In the article results of researches of influence of food supplement allocated of a guelder-rose (Viburnum sargentii Koehne) on structural and physiological characteristics of erythrocytes are presented to blood of the doctors-surgeons who are exposed during of the working day to complex stressful influence (psychologic-emotional, chemical, intensity of labour process, etc). It is shown that preventive application a polyphenolic complex from a guelder-rose promoted restoration of average volume and diameter of erythrocytes, normalization of a parity of quantitative structure of neutral lipids and phospholipids, to preservation of permeability of membranes. The food supplement allocated of a guelder-rose can be used in a treatment and prophylactic feed.

[Biologically active additives in health prophylaxis of medical workers].

The aim of the investigation was to use the biologically active additive (BAD) Kalifen to prevent metabolic disturbances in medical workers during their occupational activity. Female physicians aged 40-50 years were examined. Group 1 (control) included 20 age-matched healthy female donors. Group 2 comprised 27 female physicians (anesthesiologists and surgeons) daily exposed to stresses (chemical, psychoemotional, work-related, etc.) who were asked after blood biochemical tests to daily take the BAD Kalifen in a dose of 2.5 ml after a meal (they made up Group 3), which is equal to the daily prophylactic dose in 100 mg of total polyphenols. The plasma tested before an experiment showed hypertriglyceridemia and hypercholesterolemia, suppressed hepatic etherifying function, imbalance of the fractional content of phospholipids, exhaustion of the antioxidative system, increased lipid peroxidation, and impaired erythrocytic membrane permeability. The prophylactic use of the BAD Kalifen eliminates stress-induced metabolic disturbances and increases occupational and biological longevity in the able-bodied population.

[Alternative and non-alternative processes of the origin of chromosome aberrations]. / Al'ternativnye i neal'ternativnye protsessy vozniknoveniia aberratsii khromosom.

Five differences that form the basis for chromosome aberrations division into exchanges and fragmentations are described. A fragmentation is a more variable component of aberrations that sometimes exhibit the properties of incompleteness. The period of exchanges formation is determined. In most objects, it lasts for about 4 h on an average. Osteichthyes have additional long-term patterns of cytogenetic changes occurrence which, in all appearance, favor the evolutionary processes in this group of vertebrates.