ABSTRACT
A 24-year-old woman with a history of hydatid disease of the lung and brain, which was treated surgically and medically with albendazole, was admitted because of syncope. Echocardiography demonstrated a mass in the anterolateral papillary muscle and chordae tendineae. Despite negative serologic tests for Echinococcus granulosus, cytology and histology of the surgically removed mass confirmed hydatid disease. The patient was discharged and treated further with albendazole and praziquantel.
Subject(s)
Chordae Tendineae/diagnostic imaging , Echinococcosis/diagnostic imaging , Echinococcus granulosus/isolation & purification , Echocardiography/methods , Heart Diseases/diagnostic imaging , Papillary Muscles/diagnostic imaging , Albendazole/therapeutic use , Animals , Cardiac Surgical Procedures/methods , Chordae Tendineae/pathology , Combined Modality Therapy , Echinococcosis/diagnosis , Echinococcosis/drug therapy , Echinococcosis/surgery , Female , Follow-Up Studies , Heart Diseases/drug therapy , Heart Diseases/surgery , Humans , Papillary Muscles/pathology , Praziquantel/therapeutic use , Syncope/diagnosis , Syncope/etiology , Treatment Outcome , Young AdultABSTRACT
Secondary pulmonary hypertension is a frequent condition after heart valve surgery. It may significantly complicate the perioperative management and increase patients' morbidity and mortality. The treatment has not been yet completely defined principally because of lack of the selectivity of drugs for the pulmonary vasculature. The usage of inhaled milrinone could be the possible therapeutic option. Inodilator milrinone is commonly used intravenously for patients with pulmonary hypertension and ventricular dysfunction in cardiac surgery. The decrease in systemic vascular resistance frequently necessitates concomitant use of norepinephrine. Pulmonary vasodilators might be more effective and also devoid of potentially dangerous systemic side effects if applied by inhalation, thus acting predominantly on pulmonary circulation. There are only few reports of inhaled milrinone usage in adult post cardiac surgical patients. We reported 2 patients with severe pulmonary hypertension after valve surgery. Because of desperate clinical situation, we decided to use the combination of inhaled and intravenous milrinone. Inhaled milrinone was delivered by means of pneumatic medication nebulizer dissolved with saline in final concentration of 0.5 mg/ml. The nebulizer was attached to the inspiratory limb of the ventilator circuit, just before the Y-piece. We obtained satisfactory reduction in mean pulmonary artery pressure in both patients, and they were successfully extubated and discharged. Although it is a very small sample of patients, we conclude that the combination of inhaled and intravenous milrinone could be an effective treatment of secondary pulmonary hypertension in high-risk cardiac valve surgery patient. The exact indications for inhaled milrinone usage, optimal concentrations for this route, and the beginning and duration of treatment are yet to be determined.
Subject(s)
Heart Valve Prosthesis Implantation/adverse effects , Hypertension, Pulmonary/drug therapy , Milrinone/administration & dosage , Postoperative Complications/drug therapy , Administration, Inhalation , Aortic Valve/surgery , Female , Humans , Injections, Intravenous , Middle Aged , Mitral Valve/surgeryABSTRACT
Embolisation of coronary artery from cardiac myxoma is very rare and it is not clear what happens with embolic material inside coronary artery after myocardial infarction. The natural course of myxomatous embolus is important because it determines the mode of surgical intervention. Different options of the course of embolus have been speculated, from spontaneous resorption to growth at artery wall. We report a case of embolisation of the circumflex artery trifurcation from a villous left atrial myxoma. The course of the embolus was displayed by coronary angiography repeated 6 months after myocardial infarction. Unlike the previously published case report, we found the embolus to be unremitting.
