[Synthesis of lipoxygenase inhibitors. 1. Synthesis of open-ring amidrazones]. / Synthese von Lipoxygenaseinhibitoren. 1. Mitteilung: Synthese von offenkettigen Amidrazonen.

The synthesis of some amidrazones as bioisosteric diazaallyl radicals is described starting from the reaction mechanism of the lipoxygenases which postulates the existence of a radical after hydrogen abstraction from the arachidonic acid, N1,N3-diaryl-, N1-aryl-N3-alkyl-benzamidrazones and N1-arylacetamidrazones are strong inhibitors of the soja lipoxygenase.