1.
J Bacteriol
; 185(11): 3469-72, 2003 Jun.
Article
in English
| MEDLINE
| ID: mdl-12754247
ABSTRACT
The frequencies of nonselected mutations among adaptive Lac(+) revertants of Escherichia coli strains with and without the error-prone DNA polymerase IV (Pol IV) were compared. This frequency was more than sevenfold lower in the Pol IV-defective strain than in the wild-type strain. Thus, the mutations that occur during hypermutation are due to Pol IV.