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Structural Organization of Cerebral Basolateral Nucleus of the Amygdaloid Complex in WAG-Rij Rats with Different Genotypes by the TAQ 1A Locus of Dopamine 2 Receptor Gene (DRD2).

Akhmadeev, A V; Leushkina, N F; Kalimullina, L B.

Bull Exp Biol Med ; 162(1): 89-92, 2016 Nov.

Article in English | MEDLINE | ID: mdl-27878728

ABSTRACT

Anxiety levels and structural organization of the basolateral nucleus of the amygdaloid complex were analyzed in WAG/Rij rats with genotypes A1/A1 and A2/A2 by DRD2 locus Taq 1A. Association of anxious behavior with A2/A2 genotype and the relationship between the structural organization of the nucleus and polymorphic variants of this locus are detected.

Subject(s)

Anxiety/genetics , Depression/genetics , Epilepsy, Absence/genetics , Genetic Loci , Genotype , Receptors, Dopamine D2/genetics , Animals , Anxiety/metabolism , Anxiety/pathology , Basolateral Nuclear Complex/metabolism , Basolateral Nuclear Complex/pathology , Behavior, Animal , Cell Count , Depression/metabolism , Depression/pathology , Dopamine/metabolism , Epilepsy, Absence/metabolism , Epilepsy, Absence/pathology , Female , Gene Expression , Male , Maze Learning , Neurons/metabolism , Neurons/pathology , Rats , Receptors, Dopamine D2/metabolism

ABSTRACT

Subject(s)

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