ABSTRACT
OBJECTIVE: The aim of our study was to define he best delay for management of spontaneous rupture of the membranes at term. MATERIALS AND METHODS: We conducted a prospective multicentric study in western France defining 3 groups of expectancy (6, 12 and 24 hours) to assess obstetrical, neonatal and maternal outcomes. RESULTS: We included 713 patients. There was no significant difference in neonatal and maternal morbidity between the 3 groups. The rate of cesarean section was statistically higher in the 6-hour group (12%). There was no statistical difference between 12 and 24 hours but the rate was lower in the 12-hour group (5.5 versus 7.9%). CONCLUSION: Based on our findings and a review of the literature, we have decided that in cased of premature rupture of the membranes at term, a 12 hour delay is best. At most two prostaglandin maturations can be performed in unfavorable cervixes.
Subject(s)
Fetal Membranes, Premature Rupture/therapy , Labor, Induced/methods , Adult , Cesarean Section/standards , Cesarean Section/statistics & numerical data , Clinical Protocols/standards , Female , Fetal Membranes, Premature Rupture/complications , Fetal Membranes, Premature Rupture/diagnosis , France/epidemiology , Humans , Labor, Induced/standards , Labor, Induced/statistics & numerical data , Morbidity , Patient Selection , Pregnancy , Pregnancy Outcome/epidemiology , Prognosis , Prospective Studies , Time FactorsABSTRACT
The present data show that the contraceptive studied, a triphasic combination pill with gestodene, strongly depresses gonadotropin levels. Seric levels of both FSH and LH are below 1 mIU/ml as early as the third treatment cycle. Recovery of a normal pituitary function occurs rapidly after the administration is discontinued: both basal and stimulated gonadotropin levels are back to normal during the first cycle following a 3 months treatment course. Prolactin secretion remains unaltered both during and after treatment.