[STANDARD TRANSCUTANEOUS AND ULTRA-MINI TRANSCUTANEOUS NEPHROLITHOTRIPSY IN TREATMENT OF NEPHROLITHIASIS].

Comparative analysis of two variants of transcutaneous nephrolithotripsy (TCNLT) in 45 patients, suffering nephrolithiasis, was performed. In 17 patients (the first group) the ultra-mini (UM) TCNLT, using tubus 11Сh, was done, and in 28 patients (the second group) ­ TCNLT, using a standard tubus 24Сh. The operation duration in the first group have had constituted (86.2 ± 16.3) min at average, and in the second group ­ (51 ± 13.6) min. The method of UМ TCNLT is a secure, miniinvasive, owing low rate of morbidity, comparing with a standard procedure, but with equal efficacy, concerning the «stone free¼ status (accordingly, 95.3 and 96.5%) in patients when calculi's diameter up to 2 sm. Тubus 11Ch guarantees lesser risk of hemorrhagic complications occurrence, permits to conduct UM TCNLT without nephrostomic draining of the renal calyx and pelvis system more confidently.

[ОPTIMIZATION OF EXAMINATION ALGORITHM FOR PATIENTS BEFORE AND AFTER OPERATIVE INTERVENTION FOR HYDRONEPHROSIS].

Algorithm of the patients examination, suffering hydronephrosis, caused by obstruction of different etiology, was optimized, what permitted, using qualification of rational volume and sequence of diagnostic methods, owing high sensitivity and specificity, as well as morphological diagnostic coefficients (parenchymal­stromal, dysbalance of collagens) and the risk criterion for recurrence occurrence, to estimate renal structure­ functional state, to determine the disease stage, its course severity and to substantiate a volume and duration of preoperative preparation needed, the operative intervention kind and postoperative management of the patients.

[GIS: CAPABILITIES OF DATA ANALYSIS OF PHENO- AND GENOTYPING Of EL TOR 01 SEROGROUP CHOLERA VIBRIOS ISOLATED FROM AQUATIC OBJECTS OF THE ENVIRONMENT IN RUSSIA FEDERATION].

AIM: Application of the authors' GIS <> for systematization of atoxigenic strains ofserogroup 01 choleravibrios (ctxAB-tcpA-, ctxAB-tcpA+), isolated from aquatic objects of the environment by pheno- and genotype. MATERIALS AND METHODS: A sample of 304 Vibrio cholerae 01 strains was studied. Isolation of 39 genes related to pathogenicity was carried out Discrimination ability of a set of genes was determined by Simpson formula. Cluster analysis was carried out by UPGMA method. RESULTS: Analysis of multi-year data on aquatic V cholerae Ο1 strains in country's subject was carried out using GIS. Apossibility of systematization ofphenotypes of the isolated strains by defined parameters was shown. An experimental program for detectior of presence/lack ofvarious genes and their combinations for genotyping was developed. Conclusion GIS was established to allow to carry out analysis of phenotypes by defined parameters, as well as implement approximate systematization of genotypes of atoxigenic strains of cholera vibrios Ο1 by optimally sufficient detection of 14 genes.