[Prevention of suppurative inflammatory complications in traumatology]. / Profilaktika gnoino-vospalitelhykh oslozhnenii v travmatologii.

On the basis of the data of clinical, bacteriologic, immunologic investigations, the system for prevention of purulent-inflammatory complications (PIC) in treatment of closed and open fractures of the extremities has been developed. Use in the clinic of a system for prophylaxis permitted to reduce the incidence of PIC development in operative treatment of closed fractures from 5.6 to 1.64%, after performance of the emergency operations for open injuries--from 18.3 to 5.4%.

[Deforming gonarthrosis (questions of pathogenesis)]. / Deformiruiushchii gonartroz (nekotorye voprosy patogeneza).

Based on the biochemical, morphological, radionuclide, electron microscopy and arthroscopic data it has been established that there are significant changes in collagen proteins of the joint cartilage in the first stage of gonarthrosis deformans when degenerative and dystrophic alterations can only be seen in the joint cartilage. The determination of type II collagen which is commonly called procollagen brings something new in the understanding of the mechanism of degenerative dystrophic alterations in the joint cartilage. A considerable increase of a local proteolytic activity has been ascertained, which should be considered as the result of deep redox processes in the cartilage tissue. Gonarthrosis-associated microcirculatory disorders in the epiphyses with the development of vascular stasis, thrombosis, mural and total erythrocyte microaggregation cells, and perivascular hemorrhages have been confirmed. For the first time two forms of gonarthrosis (acute and latent) have been defined arthroscopically. The pathogenetic treatment methods have been elaborated in terms of the stages of the morphological changes identified.

[Changes in the synovial medium in deforming gonarthrosis]. / Izmeneniia sinovial'noi sredy pri deformiruiushchem gonarthroze.

The authors have determined the changes in the synovial medium of the joint characteristic of various stages of severity of the disease in 248 patients with deforming gonarthrosis on the basis of arthroscopic and thermographic studies and investigation of the permeability of the synovial membrane in the complex with clinical and roentgenologic examinations. At the initial stages the signs of local reactive inflammation of the synovial membrane near the foci of degeneration of the articular cartilage prevail. For the late stages a trend to spreading of the reactive inflammation of the synovial membrane with the development of sclerotic changes in the previously affected areas is characteristic. A comparison of the results of arthroscopy, infra-red thermography and the permeability of the synovial membrane point at parallel changes in the synovial medium and in the microcirculatory and regional circulation of the knee joint. These findings may be used for working out the rational tactics of treatment of the patients with deforming gonarthrosis.

[Osteotomy in the complex treatment of coxarthrosis]. / Osteotomiia v komplekse lecheniia koksartroza.

The author presents the substantiation of the use of intertrochanteric osteotomy of the femur in 174 patients with coxarthrosis. On the basis of clinical, roentgenologic and biomechanical data two basic operations are recommended: Pauwels-I and Bombelli, which together with various supplements depending on the stage, the form, the age and other peculiarities bring stable positive results within 10 and more years.

[Clinical, x-ray and arthroscopic parallels in initial stages of deforming arthrosis of the knee joint]. / Kliniko-rentgeno-artroskopicheskie paralleli pri nachal'nykh formakh deformiruiushchego artroza kolennogo sustava.

The study is based on the results of a clinical, roentgenologic and arthroscopic examination of 166 patients at the early stages of development of deforming arthrosis of the knee joint. The peculiarities of the early clinical, roentgenologic and arthroscopic symptoms and their relationship with the causative factors of the development of the disease have been investigated. The parallels between clinical and roentgenologic manifestations have been determined with regard to the degree of the degree of the degenerative and dystrophic changes in the articular cartilage, which is of major importance for the early diagnosis and the development of rational treatment of this pathologic condition.

[Functional anatomy, diagnosis and treatment of chronic instability of the knee joint]. / Funktsional'naia anatomiia, diagnostika i lechenie khronicheskoi nestabil'nosti kolennogo sustava.

On the basis of results of anatomical experimental, biomechanical investigations and 285 clinical observations, a new approach to the understanding of the problem of instability of the knee joint is suggested. It was proved, that instability of a joint developed in damage to a number of its structures. A classification of the anteromedial and anterolateral instability has been developed.