ABSTRACT
A 62-year-old male presented with a large non-tender mass in the glabella, extending into the right orbit that had been steadily growing for 6 months. Imaging revealed a 2.5 x 1.8 cm cystic mass with extension into the right anterior orbit. Biopsy with microscopic examination revealed a predominantly myxoid stroma containing spindle-shaped cells with bipolar cigar-shaped nuclei and small caliber capillary-type vascular proliferations. These findings are consistent with an angiomyxoma. Although angiomyxomas typically present in the pelvic region or peritoneum in female patients, there have been rare examples of angiomyxomas with orbital involvement.
Subject(s)
Myxoma/diagnosis , Orbital Neoplasms/diagnosis , Biopsy , Diagnosis, Differential , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Myxoma/pathology , Orbital Neoplasms/pathology , Tomography, X-Ray ComputedABSTRACT
The purpose of this report is to detail the clinical and histologic findings of a rare trichoadenoma of the eyelid. A 63-year-old male with a recurrent left lower eyelid lesion underwent a shave biopsy with inconclusive results until referred to an oculoplastic surgeon. The patient presented with a lesion suspicious for sebaceous cell carcinoma of the eyelid. An excisional biopsy was performed, and the specimen was sent for permanent section histologic analysis. The results revealed the lesion to be a trichoadenoma of the eyelid. The remaining lesion was excised, and the lower eyelid was reconstructed.
Subject(s)
Adenocarcinoma, Sebaceous/diagnosis , Adenoma/diagnosis , Eyelid Neoplasms/diagnosis , Sebaceous Gland Neoplasms/diagnosis , Adenoma/surgery , Blepharoplasty , Diagnosis, Differential , Eyelid Neoplasms/surgery , Humans , Male , Middle AgedABSTRACT
SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness maps. Forty-three patients with various retinal pathologies and 113 normal subjects were imaged using Cirrus HD-OCT. Reduced B-scan density was associated with increased interpolation error in ETDRS macular thickness plots. Correcting for individual differences in axial length revealed modest errors in retinal thickness maps, while more pronounced errors were observed when the ETDRS plot was not positioned at the center of the fovea (which can occur as a result of errant fixation). Cumulative error can exceed hundreds of microns, even under "ideal observer" conditions. This preventable error is particularly relevant when attempting to compare macular thickness maps to normative databases or measuring the area or volume of retinal features.
