ABSTRACT
The article describes the results of examination of 42 patients with inflammatory periodontal disease (IPO) and insulin-dependent diabetes mellitus (IDDM). It is shown, that the effect of treatment of IPO depends on a degree of compensation of carbohydrate metabolism: it is quite satisfactory in compensated and unsatisfactory in decompensated IDDM. In saliva of patients with IPO the antigen of damaged periodontal tissues, antibody to it, and also immune complexes Ag-Ab are found. The frequency of these parameters and their dynamics after treatment of IPO depends on a degree of compensation of carbohydrate metabolism in IDDM. The antibodies and immune complexes do not play a pathogenic role and can be used for prognosis and success of IPO treatment.
Subject(s)
Diabetes Mellitus, Type 1/immunology , Mouth/immunology , Periodontitis/immunology , Antigen-Antibody Complex/immunology , Carbohydrate Metabolism , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 1/metabolism , Humans , Periodontitis/complications , Periodontitis/metabolism , Periodontitis/therapyABSTRACT
The paper submits the results of studies on the combined effect of a single external (3 Gy) and chronic internal (90Sr, 11.1 X 10(5) Bq/kg/day) X-irradiation and physical exercises of different kind and intensity on some indices of nonspecific protection and immunity of albino mongrel rats and mice. Moderate physical exercises preceding irradiation diminish radiation injury to the parameters under study while intensive exercises and stress may aggravate the damages.