ABSTRACT
Clinical and experimental studies showed a high therapeutic activity of L-DOPA in combination with traditional methods of infarction treatment. L-DOPA promoted a rapid disappearance of heart failure symptoms and accelerated reparative processes by restoring the activity of the sympathetic nervous system. Correctness of the experimentally developed basically new scheme for administration of neurotropic drugs to patients with infarction depending on the disease stage has been validated.
Subject(s)
Levodopa/therapeutic use , Myocardial Infarction/drug therapy , Adult , Catecholamines/urine , Drug Evaluation , Drug Therapy, Combination , Hemodynamics/drug effects , Humans , Male , Middle Aged , Myocardial Infarction/physiopathology , Myocardial Infarction/urine , Plethysmography, Whole Body , Remission InductionSubject(s)
Amitriptyline/poisoning , Antidepressive Agents/adverse effects , Carbazoles/adverse effects , Depressive Disorder/drug therapy , Heart Block/chemically induced , Suicide, Attempted/psychology , Adult , Antidepressive Agents/administration & dosage , Carbazoles/administration & dosage , Depressive Disorder/chemically induced , Drug Synergism , Electrocardiography , Female , Heart Block/diagnosis , Humans , Time FactorsSubject(s)
Cardiomyopathies/etiology , Diabetes Complications , Adolescent , Adult , Female , Humans , MaleSubject(s)
Coronary Disease/etiology , Graves Disease/complications , Adolescent , Adult , Age Factors , Angina Pectoris/etiology , Female , Humans , Male , Middle AgedABSTRACT
Two groups of patients with myocardial infarction in conjunction with diabetes mellitus and with myocardial infarction without diabetes mellitus, similar as regards their sex and age and not suffering from hypertensive disease (a total of 165 persons) were subjected to a clinico-statistical analysis. A number of factors characterizing the clinical course of myocardial infarction and diabetes mellitus in these two groups were compared. It was found that the nature and localization of pain showed not significant differences in the patients of the study groups. However, the duration of the algetic history was much longer in patients suffering from myocardial infarction combined with diabetes mellitus. In such patients complications develop more often and run a more severe course. In most of them the onset of myocardial infarction was attended by an exacerbation of diabetes mellitus and in some cases diabetes becomes apparent for the first time at the time of myocardial infarction.
