Tinnitus complaint behaviour in long-standing Menière's disorder: its association with the other cardinal symptoms.

OBJECTIVE: To explore factors that determines tinnitus complaint behaviour in patients with chronic long-standing Menière's disorder. DESIGN AND SETTING: A questionnaire-based cross-sectional investigation. This included the Oto-neurological questionnaire, the Hearing Disability and Handicap Scale (HDHS), Hearing Measurement Scale (HMS) on sound localisation and the Dizziness Handicap Questionnaire (DHQ). PARTICIPANTS: Randomly selected 183 members of the Finnish Menière's Federation. INTERVENTION: Postal questionnaire. MAIN OUTCOME MEASURE: International Tinnitus Inventory and impact of tinnitus. RESULTS: The 183 patients,[36 men and 147 women; mean age, 63 years] had their Meniere's disorder-like symptoms, with a mean of 18 years [range, 1-43], 19% of patients ranked tinnitus as their most severe symptom, and 10% experienced tinnitus as causing a severe or very severe impact. Regression analysis indicated that 41% of International Tinnitus Inventory variance and 28% of tinnitus impact variance were explained by the cardinal symptoms of Menière's disorder. Furthermore, 40% of International Tinnitus Inventory and 25% of tinnitus impact variance were explained by symptom-related disabilities (HDHS, HMS and DHQ). Aural pressure, hearing loss and gait problems were the most important predictors of tinnitus complaint. Understanding what people say and limitation of activities because of vertigo were the most important related disabilities. CONCLUSION: Tinnitus shares a significant variance with the other cardinal symptoms in patients with long-standing Menière's disorder. As the impact is significantly related to activity limitations based on hearing disability and vertigo, the results suggest that therapeutic efforts to reduce tinnitus in Menière's disorder should include the alleviation of balance and hearing problems.

Subclinical vestibulocerebellar dysfunction in migraine with and without aura.

OBJECTIVE: In patients with migraine, neurotologic symptoms and signs occur commonly. The authors' aim was to determine whether neurotologic findings are in accordance with the type of migraine and whether test findings differ from those of healthy controls. METHODS: The authors examined 36 patients with various types of migraine classified by International Headache Society criteria. Comprehensive neurotologic tests were performed between attacks: video-oculography (VOG), electronystagmography, static posturography, and audiometry on 12 patients with migraine with aura (MA) and 24 patients with migraine without aura (MO). Results were compared to those of test-specific nonmigrainous control groups. Only eight migraineurs (six with MA and two with MO) had vertigo or dizziness. RESULTS: Despite the absence of clinical neurotologic symptoms, most of the patients with migraine (83%) showed abnormalities in at least one of these tests. Both migraine types differed significantly from the control group (in VOG, in saccadic accuracy, and in static posturography). Vestibular findings tended to be more severe in MA than in MO. CONCLUSIONS: These data suggest that interictal neurotologic dysfunction in MA and MO share similar features and that the defective oculomotor function is mostly of vestibulocerebellar origin.

Causes of persistent postoperative headache after surgery for vestibular schwannoma.

Our aim was to elucidate the aetiology of persistent postoperative headache, a common sequel for several years after vestibular schwannoma surgery through the retrosigmoid approach. Twenty-seven patients with reported major postoperative headache were tested for vestibular responses and cervico-collic reflexes. The role of local anaesthesia injected into the neck muscle insertions or around the occipital nerves was evaluated. Sixteen patients operated on for vestibular schwannoma, but without headache, and 12 healthy volunteers served as control groups. Vestibular responses and cervico-collic reflexes deteriorated equally in the patients regardless of whether or not they had a postoperative headache. Local anaesthesia did not alter the results. The posturography results were increased among both patient groups. Sumatriptan alleviated pain in nine patients and abolished it completely in one out of these nine patients. Vestibular imbalance or abnormal activation of neck muscles do not explain postoperative headache. Occipital nerve entrapment or neuralgia explains the headache in a few patients. The relatively pronounced sumatriptan effect may, however, suggest a trigeminal nerve mediated cause for postoperative headache.

Postoperative headache after surgery for vestibular schwannoma.

Postoperative headache was studied among 251 patients who underwent operation for vestibular schwannoma. A questionnaire based on the McGill Pain Questionnaire and the Finnish Pain Questionnaire was sent to the patients. Twenty-one expressions describing postoperative headache were extracted with a factor analysis. The pain intensity was expressed on a visual analog scale, and the risk factors for postoperative headache were evaluated. Immediately after the operation, 154 subjects reported headache. Eighty-nine of the patients had had headache before operation, whereas 65 patients experienced headache only after operation. An average of 8.9 years after surgery, 93 patients still reported headache. Headache was a major problem for 27 subjects; 18 of the 27 had suffered from headache before operation. A retrosigmoidal approach, postoperative gait problems, preoperative headache, and small tumor size predicted postoperative problems with headache. When headache is present before operation, it tends to continue after operation, and if headache continues for 1 year, it usually persists without being reduced.

Is hearing preservation worthwhile in vestibular schwannoma surgery?

The purpose of the study was to evaluate the usefulness of hearing preservation in vestibular schwannoma (VS) surgery. Hearing preservation was attempted in 123 of 383 patients operated on during the years 1979 to 1993 at Helsinki University Hospital. Hearing was preserved in 47 cases. Pure-tone averages (PTA) better than 30 dB were found in 12 cases postoperatively. Seventy percent of the patients rated their hearing preservation as valuable or very valuable. Only 8% did not find hearing preservation useful. Postoperatively, tinnitus was present in 62% of the patients, and it was a moderate problem in only 23% of the patients. In only one subject was the tinnitus a handicap that reduced the quality of life. Based on these experiences, we encourage surgeons to continue efforts to preserve hearing in VS surgery.

Vestibular schwannoma surgery and headache.

The aim of the study was to evaluate aetiological factors for postoperative headache after vestibular schwannoma (VS) surgery with respect to asymmetric activation of vestibular reflexes. After surgery, 27 VS patients with persistent postoperative headache, 16 VS patients without headache and 9 healthy controls were examined. The vestibular, cervicocollic and cervicospinal reflexes were evaluated to study whether asymmetric activation of vestibular reflexes could cause headache. The effect of neck muscle and occipital nerve anaesthesia and the effect of sumatriptan on headache were also evaluated. The vestibular function of VS patients with headache did not differ from that of VS patients without headache, but was abnormal when compared to that of normal controls. The cervicospinal and cervicocollic reflexes did not differ in the patient groups. Injection of lidocaine around the operation scar gave pain relief to two patients, and one of them had occipital nerve entrapment. Infiltration of lidocaine deep in the neck muscles in the vicinity of the C2 root did not alleviate headache, but caused vertigo. Nine patients with musculogenic headache got pain relief from supportive neck collars, and two patients with cervicobrachial syndrome got pain relief from manual neck traction. The study shows that asymmetric activation of cervicocollic reflexes does not seem to be the reason for headache. Headache seems to be linked to neuropathic pain, allegedly caused by trigeminal irritation of the inner ear and the posterior fossa, which has recently been linked to vascular pain.

Tinnitus and vestibular schwannoma surgery.

The aim of this study was to evaluate the effect of operation on tinnitus in vestibular schwannoma (VS) patients. Altogether, 251 VS patients who underwent surgery during the years 1979 to 1993 at Helsinki University Central Hospital were included in the study. Information on preoperative tinnitus was collected from previously acquired data and postoperative tinnitus was evaluated. Preoperatively, 62.6% of the patients had experienced tinnitus. Of those with preoperative tinnitus, 47.4% also had it postoperatively, but of those 93 patients without preoperative tinnitus, 39.8% had tinnitus postoperatively. Tinnitus is one of the primary symptoms of VS, together with hearing impairment and disequilibrium. The risk of postoperative tinnitus is almost 40%, and with preoperative tinnitus, the risk is 7.6% higher. In the majority tinnitus was not related to the surgery. Only a few patients had severe problems with tinnitus; difficulty understanding speech was the major complaint.

Non-surgical treatment of vestibular schwannoma patients.

The aim of the study was to evaluate the course of vestibular schwannoma (VS) when surgery was not attempted. The tumor may be slowly growing and surgery a risk for a patient. Twenty-eight patients out of 390 VS patients during years 1981-1995 were primarily recommended a non-surgical treatment. Another 3 patients refused the operation. Altogether 23 women and 8 men were evaluated. Their age varied from 30.6 to 74.6 years (median 56.7 years). Tumor size varied from 5 to 30 mm (median 15.0 mm) at the beginning of the follow-up. Patients symptoms, condition and other illnesses were recorded. Seven patients had neurofibromatosis 2 (3 of them had one hearing ear), 2 had severe mental problems, 5 patients had their only hearing ear and 11 patients were not recommended an operation because of their age and other illnesses. Patients were controlled with MRI at intervals from 1 to 3 years. The follow-up time varied from 1 to 20 years (median 2.0 years). The average tumor growth rate among unilateral VS patients was 0.035 cm/year and among bilateral tumors the average tumor growth rate was 0.015 cm/year. Two patients were later operated on, one 2 years after diagnosis because of the tumor growth and the other one 4 years after diagnosis-she had refused an operation earlier. Two patients could not be reached. Another patient had tumor growth but because of his illnesses he got a radiation beam instead of an operation. The majority of the patients could live fairly normal lives and required no treatment. Surgery is not the only alternative to VS patients. Wait-and-see policy is also a good alternative to those who have high operation risk or who refuse an operation.