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Mech Dev ; 84(1-2): 153-6, 1999 Jun.
Article in English | MEDLINE | ID: mdl-10473131

ABSTRACT

Although macrophage migration inhibitory factor (MIF) was originally identified as a lymphokine that inhibits the migration of macrophages, its ubiquitous expression suggests it may have a role beyond the immune system. Here we report a detailed characterization of MIF expression during mouse embryogenesis. The MIF expression pattern was found to parallel tissues specification and organogenesis.


Subject(s)
Gene Expression Regulation, Developmental , Macrophage Migration-Inhibitory Factors/genetics , Macrophage Migration-Inhibitory Factors/metabolism , Animals , Animals, Newborn , Liver/embryology , Liver/metabolism , Male , Mesoderm/metabolism , Mice , Muscle Development , Muscle, Skeletal/embryology , Muscle, Skeletal/growth & development , Muscle, Skeletal/metabolism , Muscle, Smooth/embryology , Muscle, Smooth/growth & development , Muscle, Smooth/metabolism , Nervous System/embryology , Nervous System/metabolism , Testis/embryology , Testis/metabolism
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