ABSTRACT
The aim of this study was to evaluate an effect of Broncho-Vaxom treatment on T and B lymphocytes and serum alpha 1AT in children treated at "Zuch" sanatorium in Szczawno-spa. The trial involved 46 school aged children suffering from infectious or infectious-atopic asthma. The post-Broncho-Vaxom treatment values for T lymphocytes were significantly higher in infectious, and significantly lower for B lymphocytes in infectious-atopic asthma. Serum alpha 1AT activity in children suffering from infectious asthma decreased significantly after the treatment. A correlation between the efficacy of the treatment and the lymphocyte percentage was observed. In children with very effective clinical results of Broncho-Vaxom treatment, the significant increase in T lymphocyte, and decrease in B lymphocyte populations was observed. Changes in T and B lymphocyte percentage were analysed in respect to alpha 1AT pre-treatment activity. In children with high alpha 1AT value, T lymphocytes after the treatment increased significantly in infectious, and B lymphocytes decreased significantly in infectious-atopic group.
Subject(s)
Adjuvants, Immunologic/therapeutic use , Asthma/drug therapy , B-Lymphocytes/drug effects , Bacteria , Cell Extracts , T-Lymphocytes/drug effects , alpha 1-Antitrypsin/metabolism , Asthma/blood , Child , Female , Humans , MaleSubject(s)
Barbiturates/blood , Models, Biological , Administration, Oral , Adult , Barbiturates/administration & dosage , Female , Humans , Injections, Intravenous , Male , Poland , Time FactorsSubject(s)
Asthma/complications , Enuresis/etiology , Adolescent , Asthma/drug therapy , Child , Child, Preschool , Cromolyn Sodium/therapeutic use , Enuresis/therapy , Female , Humans , MaleSubject(s)
Asthma/immunology , Hypersensitivity, Delayed/immunology , Adolescent , Cell Migration Inhibition , Child , Female , Humans , Leukocytes/immunology , MaleSubject(s)
Adjuvants, Immunologic/therapeutic use , Asthma/therapy , Bacteria , Cell Extracts , Child , Female , Humans , MaleSubject(s)
Asthma/physiopathology , Somatotypes , Adolescent , Anthropometry , Child , Female , Growth , Humans , MaleSubject(s)
Asthma/physiopathology , Growth , Sexual Maturation , Adolescent , Age Factors , Child , Female , Humans , Male , PolandSubject(s)
Pregnanediones/metabolism , Adult , Biological Availability , Half-Life , Humans , Pregnanediones/bloodABSTRACT
Experimental studies were carried our on children with extrinsic, intrinsic and mixed type asthma, treated balneologically in a sanatorium. Serum concentrations of immunoglobulins A, G, M, E and D, and serum enzyme inhibitor alpha1-antitrypsin were determined. The results were compared with those obtained in healthy children, and were also analysed in aspects of clinical and aetiological classification of asthma. Authors observed the therapeutic benefit of balneological treatment in childhood asthma. Asthmatic symptoms in children disappeared, or were much less pronounced. Mean immunoglobulin levels, before treatment higher than in healthy children, did not change after treatment, except IgE and IgG. Clinical improvement was accompanied by a significantly increasing IgG level.
Subject(s)
Asthma/immunology , Asthma/therapy , Immunoglobulins/biosynthesis , Mineral Waters , Adolescent , Asthma/blood , Child , Female , Humans , Immunoglobulin A/biosynthesis , Immunoglobulin G/biosynthesis , Immunoglobulin M/biosynthesis , MaleABSTRACT
Serotonin content in the anterior hypothalamic area (AHA) and medial basal (MBH) hypothalamus has been estimated (by the spectrofluorometric method) throughout the course of estrous cycle in the female rats. Serotonin content has been found to decrease significantly on the day of early and late proestrous in AHA and MBH, respectively. The involvement of serotonin in the process of regulation of gonadotropin releasing hormone(s) release on the level of AHA and MBH is discussed.
Subject(s)
Estrus , Hypothalamus, Anterior/metabolism , Hypothalamus, Middle/metabolism , Hypothalamus/metabolism , Serotonin/metabolism , Animals , Diestrus , Female , Pituitary Hormone-Releasing Hormones/physiology , Pregnancy , Proestrus , RatsSubject(s)
ABO Blood-Group System , Asthma/blood , Rh-Hr Blood-Group System , Adolescent , Adult , Asthma/genetics , Child , Child, Preschool , Female , Humans , Infant , MaleSubject(s)
Asthma/enzymology , Carboxylic Ester Hydrolases/blood , Adolescent , Arginine/analogs & derivatives , Arginine/blood , Asthma/therapy , Child , Female , Health Resorts , Humans , Male , PolandABSTRACT
The author describes a 47-year-old patient in whom lingual hemiatrophy developed one month after angina. The development of hemiatrophy was preceded by occipital headaches and pain behind the ear on the side of hemiatrophy. In the differential diagnosis the author excluded inflammatory processes neoplasms and developmental anomalies and thinks that the cause of this short-lasting hemiatrophy might have been tonsillitis with compression of the nerve by the oedematous inflamed tissues with action of bacterial toxins on the nerve.
