1.
J Biomol Struct Dyn
; 15(2): 393-9, 1997 Oct.
Article
in English
| MEDLINE
| ID: mdl-9399164
ABSTRACT
Based on the amino acid sequences of endogenous peptides and X-ray spatial structure, mechanism of the in vivo proteolly degradation of bovine hemoglobin was analysed. The degradation was shown to be a multi-stage process. Its first stage is determined by the spatial organization of the native protein substrate, and the next stages-by the distribution of the electrostatic field potential of the protein fragments formed at the earlier stage.