[Assessment of the diagnostic significance of R wave amplitude changes in patients with ischemic heart disease in computer-assisted monitoring analysis of ECG during treadmill test]. / Otsenka diagnosticheskogo znacheniia izmenenii amplitudy zubtsa R u bol'nykh ishemicheskoi bolezn'iu serdtsa pri monitorno-kompiuternom analize EKG vo vremia proby na tredmile.

During treadmill exercise, 57 patients with documented coronary heart disease (CHD) were studied for the change patterns in R wave amplitudes in V5 lead by analyzing ECG on a computer. With exercise, 86% of CHD patients showed higher or no R wave amplitude changes, whereas 73.7% of healthy subjects displayed its lower changes. Increased or no R wave amplitude changes in CHD patients was accompanied by more marked quantitative ischemic parameters than their decrease. A significant correlation was found between higher R wave amplitude and extended exercise-induced myocardial ischemia. Decreased R wave amplitude was associated with local ischemic shifts. Comparison of the data obtained from the computer-assisted ECG analysis and radiocardiometric findings during the exercise test demonstrated that an increase m R wave amplitude in CHD patients was followed by higher cardiac volume, which indicated ischemic myocardial dysfunction.

[Computer analysis of the ECG during physical exercise]. / Komp'iuternyi analiz EKG pri fizicheskoi nagruzke.

Treadmill tests were performed in one hundred men below 60, with computerized assessment of their ECG data. Reduced R wave amplitude from lead V5 at maximum exercise was only noted in subjects showing no electrocardiographic evidence of ischemia. Increased R wave from lead V5 was regarded as cardiac dysfunction in response to exercise, which, in the presence of ischemic ECG changes, preceded the development of pathologic ST depression. A negative T wave from leads III and aVF on resting ECG did not correlate with abnormal exercise test results. Ventricular arrhythmias were more common in subjects with non-ischemic ECG changes during exercise.

[Effectiveness of lidocaine use in the initial period of acute myocardial infarct]. / Effektivnost' primeneniia lidokaina v nachal'nom periode ostrogo infarkta miokarda.

The efficiency of variant regimens of lidocaine management of acute myocardial infarction is compared. The need for continuous infusion of the drug throughout the first day of the attack at the rate of 1 mg per minute, and the reduction in the maximum heart rate as well as the incidence, rate and duration of the ventricular tachycardia runs are demonstrated.