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1.
Heliyon ; 10(6): e28299, 2024 Mar 30.
Article in English | MEDLINE | ID: mdl-38545190

ABSTRACT

Background: The Functional Movement Screen (FMS) is widely recognized by clinicians and trainers as a valuable tool for the prediction and prevention of training injuries in sports population. However, some studies suggested that FMS may not fully meet the needs of professional athletes. To address this, the Modified Functional Movement Screen (MFMS) has been specifically developed for athletes. Methods: A total of 527 male athletes in active service without prior training injuries 18.5 ± 1.2 years old) underwent the MFMS test, and their training injuries were monitored during a 2-year follow-up period. The ability of the MFMS to predict the risk of training injury was evaluated based on the receiver operating characteristic (ROC) curve of the total MFMS score. Binary logistic analysis was employed to examine the correlation between the 10 MFMS tests and the risk of training injury. Results: The injured group of athletes had significantly lower total MFMS scores compared to the healthy group (P < 0.001). The total MFMS score demonstrated a strong predictive ability for training injury risk, with an area under the ROC curve of 0.97 (P < 0.001). The calculated cut-off point was set at 22, yielding an odds ratio of 25.63, sensitivity of 0.94, and specificity of 0.88. Binary logistic regression analysis revealed a negative correlation between 6 MFMS tests and the risk of training injury. Conclusion: The MFMS can effectively predict the risk of training injuries. Athletes with a total MFMS score below 22 are more susceptible to experiencing injuries during training.

2.
Chem Commun (Camb) ; 59(61): 9348-9351, 2023 Jul 27.
Article in English | MEDLINE | ID: mdl-37431636

ABSTRACT

We report herein the palladium-catalysed mono-selective C-H arylation of [2.2]paracyclophane (PCP) with diverse aryl iodides in the absence of any pendant directing groups, providing straightforward and modular access to C4-arylated [2.2]paracyclophanes. Moreover, a new PCP-containing biaryl monophosphine complex could be readily obtained through further derivation of the arylated product.

3.
Org Biomol Chem ; 21(7): 1389-1394, 2023 Feb 15.
Article in English | MEDLINE | ID: mdl-36655625

ABSTRACT

We report herein a cationic iridium-catalysed thioether-directed alkyne-azide cycloaddition reaction. Diverse 2-alkynyl phenyl sulfides can undergo cycloaddition with different azides in a regioselective fashion. The reaction features high efficiency, a short reaction time, and a broad substrate scope, providing modular access to complex S-containing triazoles.

4.
Org Biomol Chem ; 20(20): 4091-4095, 2022 05 26.
Article in English | MEDLINE | ID: mdl-35522070

ABSTRACT

We describe here a Ni-catalysed deamidative fluorination of diverse amides with electrophilic fluorinating reagents. Different types of amides including aromatic amides and olefinic amides were well compatible, affording the corresponding acyl fluorides in good to excellent yields.


Subject(s)
Amides , Halogenation , Catalysis , Fluorides , Indicators and Reagents
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