ABSTRACT
We describe the cases of 2 infants with congenital babesiosis born to mothers with prepartum Lyme disease and subclinical Babesia microti infection. The infants both developed anemia, neutropenia, and thrombocytopenia, and 1 infant required red blood cell transfusion. Both infants recovered with treatment. Additional studies are warranted to define the optimal management strategy for pregnant women with early Lyme disease in geographic areas in which B microti infection is endemic.
Subject(s)
Babesia microti , Babesiosis/transmission , Coinfection/transmission , Infant, Newborn, Diseases/diagnosis , Lyme Disease/transmission , Pregnancy Complications, Infectious/microbiology , Pregnancy Complications, Parasitic/parasitology , Babesiosis/complications , Borrelia burgdorferi , Coinfection/microbiology , Coinfection/parasitology , Female , Humans , Infant , Infant, Newborn , Infant, Newborn, Diseases/microbiology , Infant, Newborn, Diseases/parasitology , Infectious Disease Transmission, Vertical , Lyme Disease/complications , Male , PregnancyABSTRACT
The need for routine sepsis evaluation in patients who have experienced an apparent life-threatening event but lack signs of infection remains controversial. To assess their risk of a serious occult bacterial infection, records were reviewed of 95 infants in whom infections were discovered during their inpatient evaluation after an apparent life-threatening event. Noted for each patient was the presence of any suggestive findings that would have prompted a physician to consider the given type of infection in the differential diagnosis. Thirty patients had bacterial infections; all but 5 had suggestive findings. The exceptions included 1 patient with pneumonia and 4 with urinary tract infections. None of the remaining 25 patients had occult bacterial infections. In patients with an apparent life-threatening event who appear well and lack signs suggestive of a serious bacterial infection, it may be possible to forego routine sepsis evaluation beyond a chest radiograph and urine culture without risking a serious missed diagnosis.
Subject(s)
Hospitals, Pediatric/statistics & numerical data , Infections/complications , Infections/diagnosis , Apnea/etiology , Bacteremia/complications , Bacteremia/diagnosis , Bacterial Infections/complications , Bacterial Infections/diagnosis , Cyanosis/etiology , Data Collection/statistics & numerical data , Diagnosis, Differential , Female , Humans , Infant , Infant, Newborn , Inpatients/statistics & numerical data , Male , Meningitis/complications , Meningitis/diagnosis , Muscle Hypertonia/etiology , Muscle Hypotonia/etiology , Respiratory Tract Infections/complications , Respiratory Tract Infections/diagnosis , Risk Factors , Sepsis/complications , Sepsis/diagnosis , Urinary Tract Infections/complications , Urinary Tract Infections/diagnosis , Virus Diseases/complications , Virus Diseases/diagnosisABSTRACT
Congenital tuberculosis is unusual, and central nervous system involvement is even more rare. We report a case of congenital tuberculosis presenting with facial palsy and purulent otorrhea.
