1.
Hong Kong Med J
; 25 Suppl 7(7): 33-36, 2019 10.
Article
in English
| MEDLINE
| ID: mdl-31761769
Subject(s)
CD4-Positive T-Lymphocytes/drug effects , CD8-Positive T-Lymphocytes/drug effects , Influenza Vaccines/pharmacology , Influenza, Human/prevention & control , Orthomyxoviridae/immunology , Animals , Cytoprotection , Female , Humans , Influenza A Virus, H1N1 Subtype/immunology , Influenza A Virus, H3N2 Subtype/immunology , Influenza A Virus, H7N7 Subtype/immunology , Influenza A Virus, H7N9 Subtype/immunology , Influenza, Human/immunology , Mice , Mice, Inbred BALB C
2.
Science
; 328(5985): 1529, 2010 Jun 18.
Article
in English
| MEDLINE
| ID: mdl-20558710
ABSTRACT
The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent reintroduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Swine experimentally infected with this reassortant developed mild illness and transmitted infection to contact animals. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted.
