ABSTRACT
Peganum harmala L. is a perennial herbaceous plant that plays critical roles in protecting the ecological environment in arid, semi-arid, and desert areas. Although the seed germination characteristics of P. harmala in response to environmental factors (i.e., drought, temperature, and salt) have been investigated, the response mechanism of seed germination to drought conditions has not yet been revealed. In this study, the changes in the physiological characteristics and transcriptional profiles in seed germination were examined under different polyethylene glycol (PEG) concentrations (0-25%). The results show that the seed germination rate was significantly inhibited with an increase in the PEG concentration. Totals of 3726 and 10,481 differentially expressed genes (DEGs) were, respectively, generated at 5% and 25% PEG vs. the control (C), with 1642 co-expressed DEGs, such as drought stress (15), stress response (175), and primary metabolism (261). The relative expression levels (RELs) of the key genes regulating seed germination in response to drought stress were in accordance with the physiological changes. These findings will pave the way to increase the seed germination rate of P. harmala in drought conditions.
ABSTRACT
Emanating from a discrete category within the lympho-hematopoietic tumor system, as established by the World Health Organization in 2008, the blastic plasmacytoid dendritic cell neoplasm constitutes an uncommon malignant hematological disorder. It is routinely misidentified on account of its conspicuous dermatological manifestation, yet may insidiously permeate bone marrow and lymph nodes, involving peripheral blood and diverse extra-nodal tissues. Instances of mammary gland encroachment are extraordinarily infrequent. The current document delineates a case of a 14-year-old female patient contending with blastic plasmacytoid dendritic cell neoplasm, whose primary symptom was a mammary nodule, and whose breast and bone marrow/blood involvement were synchronous, in attempt to increase clinical vigilance.
ABSTRACT
Spontaneous combustion characteristics are important issues for the safe operation of the wet-modified activated carbon drying process. The spontaneous combustion characteristics of activated carbon modified via liquid phase impregnation were fully investigated in this study. The modified activated carbon was prepared using columnar activated carbon and 4-amino-1,2-butanediol solution. Physical properties and surface functional group analyses were performed for activated carbon before and after modification. The ignition temperature of activated carbon before and after modification was then characterized using the methods of GB/T20450-2006, thermogravimetry-derivative thermogravimetry (TG-DTG), and TG-mass spectrometry (TG-MS). At the same time, the activation energy of activated carbon before and after modification was calculated by using thermodynamic analysis. Furthermore, a new self-designed test platform was introduced to investigate the spontaneous combustion characteristics of wet-modified activated carbon under the drying temperatures of 150, 175, 180, and 210 °C. The results show that the specific surface area of Brunauer, Emmett, and Teller (BET) is decreased by 368 m2·g-1, the total volume of pore size is decreased by 0.17 cm3·g-1, and the content of oxygen-containing functional groups is decreased by 0.071 mmol/g compared with row activated carbon. The ignition temperatures of the sample before modification characterized by the three methods are 483, 596, and 599 °C, respectively. The ignition temperatures of the sample after modification are 489, 607, and 611 °C, respectively. The activation energy of the modified activated carbon is increased by 35 kJ/mol compared to the original activated carbon. It is concluded that the temperature that triggers the modified activated carbon combustion during the drying process is between 175 and 180 °C, and the heat is mainly gathered at the longitudinal center of the combustion chamber through the investigation of spontaneous combustion experiments. The results in this study can contribute to safe production to prevent combustion in the process of modifying activated carbon during the drying process.
ABSTRACT
BACKGROUND: There is limited information on a special subtype of Acute myeloid leukemia (AML) characterized by >20% myeloblasts and >20% abnormal promyelocytes in bone marrow and peripheral blood. OBJECTIVE: The objective of the present investigation was to explore the clinical and laboratory features of seven patients with AML-M2/M3. METHOD: We retrospectively assessed cell morphology, cytochemistry, immunophenotype, cytogenetics, and clinical features of seven patients with this rare subtype of AML. RESULTS: All seven cases had thrombocytopenia, coagulation abnormalities, >20% myeloblasts and abnormal promyelocytes. The PML/RARα fusion gene was present in six patients and two patients presented a mixed PML/RARα and AML1/ETO genotype. Five cases achieved CR and two cases did not achieve remission and one case transform into AML-M2 after CR1. CONCLUSIONS: The clinical and laboratory features of seven patients with AML-M2/M3 are demonstrated in the present study, providing information on the FAB sub-classification.
