ABSTRACT
Bird strike accidents mainly occur in the airport area. Reducing bird activities through bird repeller equipment is one of the main measures to prevent bird strike. In this study, two bird species with high-risk, pigeon (Columba livia domestica) and kestrel (Falco tinnunculus), were selected as the subjects and the gas gun and directional acoustic bird repeller were selected as the evaluation objects in Shenyang Taoxian International Airport. This study aimed to examine the behavioral responses of birds at different distances during the normal operation of these equipment to explore their effective distance and effects. The results showed that the vigilant and escape behaviors of pigeons and kestrels at 10 m and 30 m away from the gas gun bird repeller which were significantly higher than those of the control, while the number of these behaviors at 50 m away was not significantly different from that of the control. Pigeons and kestrels at 50 m and 100 m away from the directional acoustic bird repeller could significantly increase their vigilant and escape behaviors, whereas the repeller could significantly cause kestrels to increase their vigilant behavior at 300 m away. We concluded that the effective bird expel distance of the gas gun was 30 m, and the directional acoustic bird repeller could effectively expel to 300 m, and that the effect of the directional acoustic bird repeller on birds was stronger than the gas gun. Our results could provide a reference for the introduction and rational use of bird expel equipment in the airports.
Subject(s)
Accidents, Aviation , Birds , Airports , Animals , HumansABSTRACT
Toll-like receptor 9 (TLR9) has been shown to have a significant role in cancer. MicroRNAs (miRNAs), a group of small non-coding RNAs that fine tune translation of multiple target mRNAs, are involved in the development and progression of human cancers. The present study was undertaken to determine the roles of TLR9 on lung cancer and whether miR-26a is involved in TLR9mediated lung cancer growth and migration. The lung cancer models were elicited by injecting human lung cancer cells into the left ventricle. The expression of TLR9 and miR-26a in lung cancer tissues obtained from lung cancer patients was increased. TLR9 ligand CpG-oligodeoxynucleotides (CpG-ODN) caused an increase in the mean tumor weight and the size of tumor mass in nude mice, and the proliferation and migration of H460 human lung cancer cells. CpG-ODN also induced an increase in the expression of miR-26a in H460 cells. The overexpression of miR-26a increased the weight and size of the tumor mass in the nude mice, and the proliferation and migration of H460 cells. Expression of phosphoinositide 3 kinase (PI3K) and phosphorylation of protein kinase B (Akt) was increased after miR-26a overexpression in the H460 cells. PI3K inhibitor wortmannin (WM) or Akt inhibitor triciribine hydrate (TCN) eliminated the increase in the proliferation and migration induced by the overexpression of miR-26a in H460 cells. These results suggested that miR-26a is involved in the TLR9mediated growth and migration of lung cancer through the PI3K-Akt signaling pathway.
