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1.
Med Sci Monit ; 20: 2788-98, 2014 Dec 24.
Article in English | MEDLINE | ID: mdl-25537115

ABSTRACT

BACKGROUND: Deficits in face emotion perception are among the most pervasive aspects of schizophrenia impairments which strongly affects interpersonal communication and social skills. MATERIAL AND METHODS: Schizophrenic patients (PSZ) and healthy control subjects (HCS) performed 2 psychophysical tasks. One, the SAFFIMAP test, was designed to determine the impact of subliminally presented affective or neutral images on the accuracy of face-expression (angry or neutral) perception. In the second test, FEP, subjects saw pictures of face-expression and were asked to rate them as angry, happy, or neutral. The following clinical scales were used to determine the acute symptoms in PSZ: Positive and Negative Syndrome (PANSS), Young Mania Rating (YMRS), Hamilton Depression (HAM-D), and Hamilton Anxiety (HAM-A). RESULTS: On the SAFFIMAP test, different from the HCS group, the PSZ group tended to categorize the neutral expression of test faces as angry and their response to the test-face expression was not influenced by the affective content of the primes. In PSZ, the PANSS-positive score was significantly correlated with correct perception of angry faces for aggressive or pleasant primes. YMRS scores were strongly correlated with PSZ's tendency to recognize angry face expressions when the prime was a pleasant or a neutral image. The HAM-D score was positively correlated with categorizing the test-faces as neutral, regardless of the affective content of the prime or of the test-face expression (angry or neutral). CONCLUSIONS: Despite its exploratory nature, this study provides the first evidence that conscious perception and categorization of facial emotions (neutral or angry) in PSZ is directly affected by their positive or negative symptoms of the disease as defined by their individual scores on the clinical diagnostic scales.


Subject(s)
Affect , Facial Expression , Schizophrenia/diagnosis , Subliminal Stimulation , Task Performance and Analysis , Adult , Case-Control Studies , Female , Humans , Linear Models , Male , Middle Aged , Reproducibility of Results , Time Factors
2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-328661

ABSTRACT

<p><b>OBJECTIVE</b>To assess the safety and efficacy of hyaluronic acid-based gel of non-animal origin (NASHA gel [Restylane]; Q-Med AB, Uppsala, Sweden)for correcting nasolabial folds in Chinese.</p><p><b>METHODS</b>Patients with moderate or severe nasolabial fold (Wrinkle Severity Rating Scale, WSRS) were recruited to receive NASHA gel injection ( < 1.5 ml). The patients were followed up for 6 months. The efficacy was assessed by physicians and patients, respectively. Adverse events (AEs) were recorded and laboratory tests were performed before and after operation.</p><p><b>RESULTS</b>86 patients were treated. 6 months after injection, improved esthetic results was assessed by patients and physicians independently. 52 AEs happened in 32 cases (37.2%). Most of them were local injection reaction and minor, which were recovered spontaneously. No systemic reaction was found.</p><p><b>CONCLUSIONS</b>NASHA gel can improve the nasolabial folds. It is very safe and tolerated.</p>


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Asian People , Hyaluronic Acid , Therapeutic Uses , Rhytidoplasty , Methods , Skin Aging
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