Subject(s)
Erythropoietin/pharmacokinetics , Anemia/drug therapy , Anemia/etiology , Anemia/metabolism , Combined Modality Therapy , Erythropoietin/administration & dosage , Erythropoietin/adverse effects , Humans , Injections, Intravenous , Injections, Subcutaneous , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/metabolism , Kidney Failure, Chronic/therapy , Recombinant Proteins/administration & dosage , Recombinant Proteins/adverse effects , Recombinant Proteins/pharmacokinetics , Renal Dialysis/adverse effects , Time FactorsABSTRACT
Immunoglobulin levels have been assayed in endometrial secretions from 30 patients with chronic, 25 patients with acute endometritis and 15 normal women. Concentrations of IgG, IgA and, especially, IgM were high in patients with chronic endometritis as compared with the normal women and patients with acute endometritis. These findings suggest that immunoglobulin studies may be used as a diagnostic and predictive test.
Subject(s)
Endometritis/immunology , Endometrium/metabolism , Immunoglobulins/analysis , Mucus/immunology , Adult , Chronic Disease , Female , HumansABSTRACT
The effect of TBG on the functional activity of different cell lines, spontaneous and Con A induced proliferation of PBL was studied. If concentration of TBG is higher than 50 mu kg/ml it suppresses the proliferation in many used cell lines, except choriocarcinoma and cancer of uterus. The reliable increasing of spontaneous proliferation of PBL, Jurkat and K-562 cells may be observed if concentration is more lower (0.5-15 mu kg/ml). However proliferation of other cell lines corresponds to control level, and Con A induced proliferation of PBL is inhibited. The effect was more marked at 48, as compared to 24 hours of cell incubation with TBG.
Subject(s)
Biomarkers, Tumor/physiology , Pregnancy-Specific beta 1-Glycoproteins/physiology , Tumor Cells, Cultured/drug effects , Biomarkers, Tumor/pharmacology , Cell Division , Cell Line/drug effects , Cell Line/physiology , Choriocarcinoma , Concanavalin A/pharmacology , Female , HeLa Cells , Humans , Leukemia, Erythroblastic, Acute , Leukemia, Myeloid , Leukemia, T-Cell , Lymphocytes/cytology , Lymphoma, B-Cell , Lymphoma, T-Cell , Pregnancy-Specific beta 1-Glycoproteins/pharmacology , Tumor Cells, Cultured/physiology , Uterine NeoplasmsABSTRACT
While analyzing M-HeLa cells by IFA technique secretory and membrane-bound forms of human placental alkaline phosphatase (HPAP) were detected. Activity of secretory HPAP increased if cell density and incubation time were increased too. After short influence of heat shock (15 min at 42 degrees C) activity of secretory HPAP increased for 45% and intracellular HPAP 3 for 37%. It is proposed that HPAP take part in organization of first response to heat shock and support cellular thermotolerance.
