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Prikl Biokhim Mikrobiol ; 22(6): 806-9, 1986.
Article in Russian | MEDLINE | ID: mdl-3101059

ABSTRACT

The effect of heat treatment used in the course of tuberculin production by Mycobacteria tuberculosis cells on the structure and biological activity of tuberculin was studied. Methods of preparative and analytical gel-filtration were used. The largest quantity of the biologically active component was obtained after 2-hour heat treatment of the mycobacteria culture.


Subject(s)
Hot Temperature , Tuberculin/isolation & purification , Bacteriological Techniques , Chromatography, Gel , Mycobacterium bovis/analysis , Mycobacterium tuberculosis/analysis
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