ABSTRACT
OBJECTIVE: To report a rare case of endometrial yolk sac tumor (YST) and review published cases of YST of the endometrium. CASE REPORT: A 68-year-old female presented with intermittent vaginal spotting for nine months. An endometrial biopsy showed adenocarcinoma. Complete surgical staging operation was performed and the final pathology revealed stage II endometrial yolk sac tumor. The post-operative α-fetoprotein (AFP) level was 133.4 ng/mL. Post-operative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin (BEP) regimen was prescribed for 6 cycles. AFP levels were normal before the fourth cycle of chemotherapy. She is disease free 6 months after completion of therapy. CONCLUSION: Primary YSTs arising in the endometrium is an extremely rare disease especially in postmenopausal women. Complete surgical staging operation with adjuvant chemotherapy will lead to good outcome in this disease.
Subject(s)
Endodermal Sinus Tumor/diagnosis , Endometrial Neoplasms/diagnosis , Aged , Antineoplastic Agents/therapeutic use , Biopsy , Chemotherapy, Adjuvant , Endodermal Sinus Tumor/therapy , Endometrial Neoplasms/therapy , Endosonography , Female , Humans , Hysterectomy/methods , Laparotomy/methods , VaginaSubject(s)
Intrauterine Devices , Retroperitoneal Space , Device Removal , Female , Humans , Laparotomy , Middle Aged , PregnancyABSTRACT
OBJECTIVE: The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation. MATERIALS AND METHODS: From 2006 to 2007, we recruited 150 pregnant women who received routine GBS culture screening at 35 weeks' gestation with negative results, and who had repeat cultures and real-time polymerase chain reaction (RT-PCR) tests for GBS after 39 weeks' gestation. RESULTS: Two percent of pregnant women with GBS-negative results by culture screening at 35 weeks' gestation were GBS-positive at 39 weeks' gestation. CONCLUSION: It is necessary to perform a GBS test 4 weeks after an initial negative GBS culture at 35-37 weeks of gestation. RT-PCR provides a simple and rapid alternative method for detecting rectovaginal GBS colonization at the time of labor.
Subject(s)
Microbiological Techniques/methods , Pregnancy Complications, Infectious/diagnosis , Reverse Transcriptase Polymerase Chain Reaction/methods , Streptococcal Infections/diagnosis , Streptococcus agalactiae/genetics , Adolescent , Adult , DNA, Bacterial/genetics , Female , Humans , Mass Screening/methods , Pilot Projects , Predictive Value of Tests , Pregnancy , Prenatal Care/methods , Prospective Studies , Sensitivity and Specificity , Streptococcus agalactiae/growth & development , Streptococcus agalactiae/isolation & purification , Young AdultABSTRACT
BACKGROUND: Cesarean scar pregnancy complicated by placenta percreta and uterine rupture is an uncommon gynecologic emergency. CASE: A woman presenting with abdominal pain and shock was found to have a cesarean scar pregnancy complicated by placenta percreta and uterine rupture. CONCLUSION: Implantation within a cesarean scar may cause placenta percreta, leading to uterine rupture in the first trimester and mimicking other gynecologic emergencies.
