ABSTRACT
OBJECTIVE: To compare the clinical effect between wheat-grain moxibustion at Yinbai (SP 1) and oral administration of dydrogesterone tablet for menstrual period prolongation after down-regulation treatment of in vitro fertilization embryo transfer (IVF-ET). METHODS: A total of 54 patients with prolonged menstrual period after down-regulation treatment of IVF-ET were randomly divided into an observation group and a control group, 27 cases in each one. In the observation group, when the menstrual period delayed more than 7 days, the wheat-grain moxibustion at Yinbai (SP 1) was performed, once a day, with an interval of 1 day between two 3-day treatments; when the menstrual blood was cleaned, the ovulation was continued and the eggs were taken. In the control group, when the menstrual period delayed more than 7 days, the oral administration of dydrogesterone tablet was provided, 10 mg each time, twice a day; when the menstrual blood was cleaned, the ovulation was continued and the eggs were taken. The number of days for menstrual blood to be cleaned, the area change of uterine cavity hemorrhage, the morphology of endometrium, the blood supply of endometrium, the number of oocytes obtained, the grade of frozen embryo and the clinical effect were observed between the two groups after treatment. RESULTS: Compared with the control group, the number of days for menstrual blood to be cleaned was shorter in the observation group after treatment (P<0.05); the area of uterine cavity hemorrhage in the observation group was smaller than that in the control group (P<0.05); the morphology of endometrium and the supply of blood flow in the observation group were superior to those in the control group (P<0.05). However, there was no significant difference in the number of oocytes obtained and available frozen embryo between the two groups (P>0.05). The cured rate in the observation group was 100.0% (27/27), higher than 33.3% (9/27) in the control group (P<0.05). CONCLUSION: The wheat-grain moxibustion at Yinbai (SP 1) could more effectively treat prolonged menstrual period after IVF-ET down-regulation treatment, which is beneficial to the preparation of the endometrium, and has no effect on the oocyte collection and embryo culture.
