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1.
Clin Interv Aging ; 14: 1119-1129, 2019.
Article in English | MEDLINE | ID: mdl-31354254

ABSTRACT

Objective: This study aims to analyze the prevalence of dyslipidemia and identify the cardiovascular disease (CVD) risk stratification among older adults living in Quanzhou, China's southeast coastal region, where the ancient Maritime Silk Road starts. Methods: A population-based cross-sectional survey of 2,018 adults was conducted in 60-98-year-old residents in Quanzhou from September 2016 to March 2018 using multistage stratified cluster random sampling. The 10-year CVD risk was also estimated by applying the Chinese model recommended by the Chinese Guidelines for Prevention of Cardiovascular Diseases. Results: The overall prevalence of dyslipidemia among older adults was 56.8%. The prevalence of high total cholesterol (TC), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) were 8.4%, 13.9%, 23.1% and 11.4%, respectively. The mean levels of TC, LDL-C, HDL-C and TG were 5.12±1.18, 3.37±0.81, 1.03±0.27 and 1.65±0.76 mmol/L, respectively. Older adults had low risk, moderate risk and high risk for CVD, which were 49.7%, 36.8% and 13.5%, respectively. Age, body mass index and abdominal obesity were significantly associated with the risk of increasing LDL-C levels and were positively correlated to CVD risk. Conclusion: The prevalence of high TC, high LDL-C, low HDL-C and high TG was relatively low among older adults in Quanzhou, but their lipid levels were high. Approximately half of the elderly adults had moderate or high CVD risk. The personalized primary prevention and control of CVD are recommended for elderly people to identify high-risk individuals.


Subject(s)
Cardiovascular Diseases/epidemiology , Dyslipidemias/epidemiology , Age Factors , Aged , Aged, 80 and over , Asian People , Body Mass Index , China/epidemiology , Cross-Sectional Studies , Female , Humans , Lipids/blood , Male , Middle Aged , Obesity, Abdominal , Prevalence , Primary Prevention , Risk Factors
2.
Zhen Ci Yan Jiu ; 37(1): 72-6, 2012 Feb.
Article in Chinese | MEDLINE | ID: mdl-22574574

ABSTRACT

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease in women of reproductive age, and the obesity and insulin resistance are considered to be the key link in the pathophysiological process of PCOS of obesity type. Adiponectin, a protein hormone, is closely related to insulin resistance and obesity, which has been being researched extensively in recent years. The authors of the present article review the pathogenesis of PCOS of obesity type from the relationship between adiponectin and obesity, and between adiponectin and insulin resistance, separately. In particular, the authors review studies on the underlying mechanism of acupuncture and moxibustion interventions in regulating adiponectin level briefly. The authors think of that acupuncture and moxibustion interventions induced increase of adiponectin level is possibly to improve insulin resistance in obesity and/or PCOS patients, hoping to provide a new target for clinical treatment of PCOS.


Subject(s)
Acupuncture Therapy , Adiponectin/genetics , Obesity/genetics , Obesity/therapy , Polycystic Ovary Syndrome/genetics , Polycystic Ovary Syndrome/therapy , Adiponectin/metabolism , Female , Gene Expression Regulation , Humans , Moxibustion , Obesity/metabolism , Polycystic Ovary Syndrome/metabolism
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