[Hendersonula toruloidea, causative agent of a fungal verrucous dermatitis observed in Algeria]. / Hendersonula toruloidea, agent d'une dermatite verruqueuse mycosique observée en Algérie.

A verrucose dermatitis of the face, accompanied by onychomycosis was observed in a 30 years old male living in Algeria. He was born there and 15 years previously he had been treated successfully for "Dermatophytic disease" due to Trichophyton verrucosum. A deficiency in his cellular immune mechanism was noted at that time. On this occasion Hendersonula toruloidea was isolated from facial lesions and affected nails. The infection of the face, but not the nails, responded to treatment with amphotericin B. In the facial lesions, the fungus was present as single cell units sometimes with a false bud or a short hyphal extension. Cross walls were occasionally present but the cell walls were not pigmented. Intratesticular inoculation of the isolates to guinea pigs resulted in an infection in which the morphology of the fungus conformed to that found in the facial lesions. In cultures, the isolates of H. toruloidea conformed to the descriptions in literature, although pycnidia were not formed.

[Blastomyces dermatitidis blastomycosis in Africa. First Algerian case]. / La blastomycose à Blastomyces dermatitidis en Afrique. A propos du premier cas Algérien

A case of fatal generalized Blastomycosis is reported. It was the first case of that mycosis observed in Algeria. The parasitic yeast-like cells of the fungus were seen in pus and tissue sections and Blastomyces dermatitidis cultured from pathological specimens. Yeast-like form was obtained in vitro on Kurung's agar at 37 degrees C. Male hamsters infected with this strain failed to develop an experimental disease. The occurrence and distribution of Blastomycosis in Africa are discussed.

[Verrucous mycotic dermatitis due to an unusual dematiaceous fungus. Clinical and histopathological discussion (author's transl)]. / Dermatite verruqueuse mycosique due a un champignon dématié inhabituel. Discussion clinique et histopathologique

A case of "verrucous dermatitis" caused by a dematiaceous fungus has been observed in an 30 y. o. Algerian patient. The lesion was localized on the face. The patient presented previously a chronic dermatophytic disease due to Trichophyton verrucosum. The dematiaceous hyphomycete has been isolated several time from superficial specimens and portions of biopsies. This fungus has been injected by intra-testicular route in guinea-pigs. The aspect of the fungus in its parasitical morphology has been described and compared with that seen in the testis: In the lesions, the vesiculous or short fungal elements are not pigmented; they are sometimes cross-walled. Successful treatment has been obtained with administration of intravenous amphotericin B. It seems that the patient is genetically predisposed and has a deficient cellular mediated immunity.