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1.
Braz. oral res ; 25(1): 80-84, Jan.-Feb. 2011. ilus, graf, tab
Article in English | LILACS | ID: lil-595843

ABSTRACT

There are many studies that evaluate possible risk factors for periodontal diseases in animals. Most of them have focused only on the biological aspects of disease occurrence; therefore, it has been difficult to compare studies of the different methodological approaches. The aim of the present study was to compare different methods - linear and area - of the evaluation of morphometrical alveolar bone loss. Sixty hemimaxillae, defleshed and stained with 1 percent methylene blue to delineate the cementoenamel junction and alveolar bone crest, were obtained from a previous study that induced periodontal disease by means of ligatures in two groups of fifteen Wistar rats during 9 weeks. Ligatures were placed around the right upper second molars, and the contra-lateral teeth remained as intra-group controls. Digital photographs were taken from the specimens and submitted to a single, calibrated, blind examiner who performed the morphometrical evaluation of alveolar bone loss using both linear and area methods. Mean values of linear and area measurements were obtained from each side - buccal and palatal - of the specimens. The degree of association between the two methods was determined by Pearson's Correlation Coefficient. An almost perfect association (0.98) was determined between the linear and area evaluations. A mathematical formula was subsequently created to estimate the total area of alveolar bone loss, from linear mean measurements. Both methods were suitable for detecting bone level alterations. The results of the present study allow for the transformation of data and better compilation of results from different studies.


Subject(s)
Animals , Rats , Alveolar Bone Loss/pathology , Periodontal Diseases/pathology , Tooth Socket/pathology , Disease Models, Animal , Image Processing, Computer-Assisted , Periodontal Diseases/etiology , Rats, Wistar , Reproducibility of Results , Time Factors
2.
Braz Oral Res ; 25(1): 80-4, 2011.
Article in English | MEDLINE | ID: mdl-21271178

ABSTRACT

There are many studies that evaluate possible risk factors for periodontal diseases in animals. Most of them have focused only on the biological aspects of disease occurrence; therefore, it has been difficult to compare studies of the different methodological approaches. The aim of the present study was to compare different methods - linear and area - of the evaluation of morphometrical alveolar bone loss. Sixty hemimaxillae, defleshed and stained with 1% methylene blue to delineate the cementoenamel junction and alveolar bone crest, were obtained from a previous study that induced periodontal disease by means of ligatures in two groups of fifteen Wistar rats during 9 weeks. Ligatures were placed around the right upper second molars, and the contra-lateral teeth remained as intra-group controls. Digital photographs were taken from the specimens and submitted to a single, calibrated, blind examiner who performed the morphometrical evaluation of alveolar bone loss using both linear and area methods. Mean values of linear and area measurements were obtained from each side - buccal and palatal - of the specimens. The degree of association between the two methods was determined by Pearson's Correlation Coefficient. An almost perfect association (0.98) was determined between the linear and area evaluations. A mathematical formula was subsequently created to estimate the total area of alveolar bone loss, from linear mean measurements. Both methods were suitable for detecting bone level alterations. The results of the present study allow for the transformation of data and better compilation of results from different studies.


Subject(s)
Alveolar Bone Loss/pathology , Periodontal Diseases/pathology , Tooth Socket/pathology , Animals , Disease Models, Animal , Image Processing, Computer-Assisted , Periodontal Diseases/etiology , Rats , Rats, Wistar , Reproducibility of Results , Time Factors
3.
Arch Oral Biol ; 56(2): 109-13, 2011 Feb.
Article in English | MEDLINE | ID: mdl-20943212

ABSTRACT

OBJECTIVE: The aim of the present study was to evaluate the influence of ethanol in low concentration (5%) in ligature-induced alveolar bone loss in Wistar rats. MATERIAL AND METHODS: Thirty rats were randomly assigned to test and control groups (n=15). Test group received a liquid diet containing ethanol 5% (vol./vol.) and standard rat chow. Control group received only tap water as the liquid diet and the same rat chow. In both groups, diet was delivered ad libitum. Alveolar bone loss was induced prior to the beginning of the study by means of ligatures placed around the upper second molars. The contra-lateral tooth remained as intra-group control. At the end of the nine weeks, the animals were killed and morphometric analysis of alveolar bone loss was performed by a blinded and calibrated examiner. Intra-group comparisons were performed by paired sample T-test and inter-group differences were compared by independent sample T-test (α=.05). RESULTS: Animals that drank ethanol in low concentration systematically presented less alveolar bone loss than the control group, regardless of the presence of ligature. Test group showed less alveolar bone loss (p=0.04) in unligated teeth when compared to control group (0.32 ± 0.07 and 0.37 ± 0.07 mm, respectively). However, no significant difference (p=0.14) was observed between Test and Control groups (0.78 ± 0.14 and 0.84 ± 0.18 mm, respectively) in ligated teeth. CONCLUSION: The results of this study lead to the conclusion that low concentration alcohol intake did not affect the alveolar bone loss in ligature induced periodontal breakdown.


Subject(s)
Alveolar Bone Loss/prevention & control , Ethanol/administration & dosage , Ethanol/pharmacology , Periodontitis/complications , Administration, Oral , Animals , Disease Models, Animal , Energy Intake , Ligation , Male , Random Allocation , Rats , Rats, Wistar , Reproducibility of Results , Risk Factors , Time Factors
4.
Braz Oral Res ; 23 Suppl 1: 56-63, 2009.
Article in English | MEDLINE | ID: mdl-19838559

ABSTRACT

Dentine hypersensitivity is a condition that is often present in individuals, leading them to seek dental treatment. It has been described as an acute, provoked pain that is not attributable to other dental problems. Its actual prevalence is unknown, but it is interpreted as very unpleasant by individuals. Several therapeutic alternatives are available to manage dentine hypersensitivity, involving both in-office treatment and home-use products. The aim of this literature review was to evaluate self-care products for managing dentine hypersensitivity. Among the products available, dentifrices and fluorides are the most studied self-care products, with positive effects. However, a high percentage of individuals is affected by the placebo effect. Among dentifrices, those containing potassium salts seem to be the most promising. Dental professionals need to understand the advantages and limitations of these therapies and use this knowledge in a positive approach that might help in decreasing dentine hypersensitivity among patients.


Subject(s)
Dental Devices, Home Care , Dentifrices/therapeutic use , Dentin Sensitivity/therapy , Fluorides/therapeutic use , Clinical Trials as Topic , Dentin Sensitivity/prevention & control , Humans , Placebos , Potassium/therapeutic use , Self Care , Strontium/therapeutic use , Toothache/etiology
5.
Odonto (Säo Bernardo do Campo) ; 17(33): 63-70, jan.-jun. 2009. ilus, tab
Article in Portuguese | LILACS, BBO - Dentistry | ID: lil-542841

ABSTRACT

O emprego da RTG na prática clínica ainda carece de evidências na literatura. Esta revisão sistemática procurou avaliar o uso de barreiras para o tratamento de lesões de furca quando comparado ao acesso cirúrgico. Foi procurado na literatura ensaios clínicos randomizados com pelo menos 6 meses de duração e que comparassem o uso da RTG com acesso cirúrgico. Quatro estudos estavam de acordo com os critérios de inclusão. Dentre estes, o percentual de fechamento de lesões de furca de grau II com a RTG apresentado por três artigos ficou entre 0 e 30%. O emprego da RTG apresenta pouca previsibilidade e vantagens modestas no tratamento de lesões de furca de grau II em molares mandibulares. Ainda não há na literatura evidência suficiente para a avaliação da RTG em lesões de furca de graus I e III.


The use of GTR in clinical practice still lacks evidence in the literature. This systematic review evaluated the use of barriers for the treatment of furcation involvements as compared to open flap debridement (OFD). The search looked for randomized controlled clinical trials with at least 6 months of follow-up, that compared the use of GTR with OFD. Four studies met the inclusion criteria. Among them, the percent of complete closure of degree II furcation defects with GTR, presented in 3 articles varied between 0 and 30%. The use of GTR has low predictability and modest advantages in the treatment of degree II furcation defects in lower molars. The literature still lacks sufficient evident to evaluate GTR in degrees I and III furcation defects.


Subject(s)
Furcation Defects/therapy , Guided Tissue Regeneration, Periodontal/statistics & numerical data , Guided Tissue Regeneration, Periodontal/methods , Gingival Recession , Periodontal Attachment Loss , Periodontal Index
6.
Braz. oral res ; 23(supl.1): 56-63, 2009.
Article in English | LILACS | ID: lil-528430

ABSTRACT

Dentine hypersensitivity is a condition that is often present in individuals, leading them to seek dental treatment. It has been described as an acute, provoked pain that is not attributable to other dental problems. Its actual prevalence is unknown, but it is interpreted as very unpleasant by individuals. Several therapeutic alternatives are available to manage dentine hypersensitivity, involving both in-office treatment and home-use products. The aim of this literature review was to evaluate self-care products for managing dentine hypersensitivity. Among the products available, dentifrices and fluorides are the most studied self-care products, with positive effects. However, a high percentage of individuals is affected by the placebo effect. Among dentifrices, those containing potassium salts seem to be the most promising. Dental professionals need to understand the advantages and limitations of these therapies and use this knowledge in a positive approach that might help in decreasing dentine hypersensitivity among patients.


Subject(s)
Humans , Dental Devices, Home Care , Dentifrices/therapeutic use , Dentin Sensitivity/therapy , Fluorides/therapeutic use , Clinical Trials as Topic , Dentin Sensitivity/prevention & control , Placebos , Potassium/therapeutic use , Self Care , Strontium/therapeutic use , Toothache/etiology
7.
Porto Alegre; s.n; 2009. 73 p. graf, ilus, tab.
Thesis in Portuguese | BBO - Dentistry | ID: biblio-865642

ABSTRACT

A relação entre o álcool e as doenças periodontais destrutivas tem sido avaliada em humanos através de estudos transversais e longitudinais na última década. As investigações apontam para resultados conflitantes sobre a influência do consumo de bebidas alcoólicas na progressão da periodontite. Em quatro estudos recentes realizados em ratos Wistar, o consumo de álcool com concentrações entre 10% e 30% esteve associado a uma maior perda óssea alveolar. Nestes estudos, os métodos de avaliação da perda óssea alveolar em estudos de modelo animal tem sido realizados de formas distintas, impedindo uma comparação direta em investigações que utilizaram diferentes concentrações de álcool. Contudo, a literatura tem correlacionado o consumo de concentrações moderadas de bebidas alcoólicas com uma melhora no sistema imunológico e uma redução em marcadores inflamatórios sistêmicos, reduzindo a ocorrência de eventos cardiovasculares e aterosclerose. O mecanismo de atuação do álcool nestes parâmetros parece ser ambíguo e dependente da dose, do padrão de consumo e de características individuais variáveis. Os resultados conflitantes sobre a relação entre consumo de bebidas alcoólicas e doença periodontal podem sugerir esse padrão bifásico do álcool. Não existem estudos em modelo animal que avaliaram o impacto da administração de concentrações menores de álcool sobre a perda óssea alveolar. A discussão acerca de metodologias...


The relationship between alcohol and periodontal disease have been evaluated in humans throughout cross-sectional and longitudinal studies in the last decade. The investigations have led to conflicting results about the influence of alcohol drinking on periodontitis progression. In four studies with Wistar rats, alcohol consumption in concentrations ranging between 10% to 30% was associated with greater alveolar bone loss. In these studies,different methods of bone loss evaluation have been used in animal model studies and it turns difficult to make a direct comparison between investigations that utilized different alcohol concentrations. However, the literature has associated moderate alcohol consumption with improvement in immunological status and reduction in inflammatory markers, reducing cardiovascular events and atherosclerosis. The mechanisms by which alcohol influences these parameters seems to be ambiguous and dependent of dose, pattern of consumption and individual characteristics. The conflicting results between beverage consumption and periodontal disease may suggest the biphasic pattern of alcohol. There aren’t studies in animal models that evaluated the impact of low alcohol concentrations on alveolar bone loss. Discussion about methodological issues and results interpretation in relation to studies in animals are...


Subject(s)
Animals , Rats , Ethanol/administration & dosage , Ethanol/adverse effects , Periodontitis , Alveolar Bone Loss , Case-Control Studies
8.
Perionews ; 2(2): 123-128, abr.-jun. 2008. tab
Article in Portuguese | LILACS | ID: lil-728167

ABSTRACT

O emprego da técnica com barreiras para a regeneração periodontal surge como uma possibilidade para o tratamento das recessões gengivais, um problema que acomete indivíduos com padrões de higiene distintos. A etiologia para ocorrência de tal problema tem sido atribuída, portanto, a fatores traumáticos durante a escovação e/ou a presença de inflamação periodontal causada pela presença de placa. Em relação ao enxerto de conjuntivo subepitelial, considerado o tratamento padrão, a técnica com barreiras evitaria a necessidade da área doadora, o que poderia reduzir a morbidade após o procedimento cirúrgico de recobrimento. Esta revisão sistemática procurou comparar o uso de barreiras para o tratamento das recessões gengivais com enxerto de conjuntivo subepitelial. O emprego da RTG com barreiras reabsorvíveis e não-reabsorvíveis mostrou resultados similares quando comparados ao enxerto conjuntivo subepitelial para o recobrimento radicular


Subject(s)
Furcation Defects/therapy , Gingival Recession , Guided Tissue Regeneration, Periodontal , Periodontal Attachment Loss , Periodontal Index
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