ABSTRACT
INTRODUCTION: Decompressive craniectomy is an alternative in cases where there is increased intracranial pressure. Bone autografts are accepted as a method of reconstruction of the skull. The aim of this paper is to describe the macroscopic and radiological findings of autologous parietal bone in rats after storage in adipose tissue as a reservoir. METHODS: We used 20 Wistar rats which underwent a craniectomy. 4 groups were formed: group I, the bone flap fat remained for 14 days, group II, the flap remained for 21 days, in group III, for 28 days and in group IV for 35 days. They were euthanized 70 days after reattached. RESULTS: When removing the flap of subcutaneous fat, a high bright whitish microvasculature and presence in 11 of the flaps. Following 70 days of re-injertarse was found that 56.25% of the animals presented terraced edges, reflecting some consolidation in the radiological analysis 31.25% of cases showed areas of consolidation. Animals in group II and III findings showed more consolidation. CONCLUSIONS: The bone flap remained viable during their stay in adipose tissue. Fibrous tissue and neovasculature were important findings that reflect the proper process of bone healing. You need the histological studies complemented biomechanics, neurological and bioacoustics.
Subject(s)
Adipose Tissue , Organ Preservation/methods , Parietal Bone/transplantation , Animals , Graft Survival , Male , Rats , Rats, Wistar , Transplantation, AutologousABSTRACT
BACKGROUND: Crying is the first neurophysiological demonstration of the newborn. The acoustic analysis of crying episodes can provide useful information in the early diagnosis of several pathologies. METHODS: We carried out a spectrographic cry analysis of 40 infants with several diseases such as neonatal asphyxia, breathing disorders, deafness and neurological disorders. Statistical t-test was used in order to compare means of fundamental frequencies (F0) of cries among pathologies, as well as contingency tables for qualitative variables and melodic form. RESULTS: No significant differences of F0 were found by applying the t-test among pathologies. Time of inspiration in breathing disorders is higher compared with other groups. Infants with deafness and neurological disorders present poor melodic forms. Qualitative analysis revealed more often glottal roll and vibrato. CONCLUSIONS: Cry analysis is clinically useful for early detection of diseases in newborns as a result of alterations in the central nervous system that are reflected in phonoarticulatory and respiratory functions for sound emission.
Subject(s)
Crying/physiology , Hearing Loss/physiopathology , Infant, Newborn, Diseases/physiopathology , Sound Spectrography , Asphyxia Neonatorum/physiopathology , Dysphonia/etiology , Dysphonia/physiopathology , Female , Hearing Loss/congenital , Humans , Infant, Newborn , Male , Nervous System Diseases/congenital , Nervous System Diseases/physiopathology , Phonation/physiology , Respiration , Respiration Disorders/congenital , Respiration Disorders/physiopathology , Risk , Speech Acoustics , Voice QualityABSTRACT
El objeto del trabajo fue analizar el comportamiento de las vocalizaciones en cobayos recién nacidos con audición normal e hipoacúsicos. Para ello se utilizaron 10 camadas de cobayos pigmentados, cada camada consistía en la madre y sus hijos viviendo en jaulas separadas. De cada camada se utilizaron a las dos hijas hembras de mayor peso a una de las cuales se le destruyeron las cócleas al nacimiento. Cinco días a la semana se registraron las vocalizaciones que emitía cada grupo (sordas o normales) hasta el día 40 post nacimiento. Para el análisis de resultados se cuantificó la cantidad de vocalizaciones que emitía cada grupo y se hicieron estudios estadísticos que mostraron diferencia significativa con p<0.05. Los resultados señalan la importancia de la retroalimentación auditiva para la evolución y desarrollo de vocalizaciones en esta especie.
