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1.
Hear Res ; 392: 107970, 2020 07.
Article in English | MEDLINE | ID: mdl-32339775

ABSTRACT

Recent sound coding strategies for cochlear implants (CI) have focused on the transmission of temporal fine structure to the CI recipient. To date, knowledge about the effects of fine structure coding in electrical hearing is poorly charactarized. The aim of this study was to examine whether the presence of temporal fine structure coding affects how the CI recipient perceives sound. This was done by comparing two sound coding strategies with different temporal fine structure coverage in a longitudinal cross-over setting. The more recent FS4 coding strategy provides fine structure coding on typically four apical stimulation channels compared to FSP with usually one or two fine structure channels. 34 adult CI patients with a minimum CI experience of one year were included. All subjects were fitted according to clinical routine and used both coding strategies for three months in a randomized sequence. Formant frequency discrimination thresholds (FFDT) were measured to assess the ability to resolve timbre information. Further outcome measures included a monosyllables test in quiet and the speech reception threshold of an adaptive matrix sentence test in noise (Oldenburger sentence test). In addition, the subjective sound quality was assessed using visual analogue scales and a sound quality questionnaire after each three months period. The extended fine structure range of FS4 yields FFDT similar to FSP for formants occurring in the frequency range only covered by FS4. There is a significant interaction (p = 0.048) between the extent of fine structure coverage in FSP and the improvement in FFDT in favour of FS4 for these stimuli. FS4 Speech perception in noise and quiet was similar with both coding strategies. Sound quality was rated heterogeneously showing that both strategies represent valuable options for CI fitting to allow for best possible individual optimization.


Subject(s)
Cochlea/physiopathology , Cochlear Implantation/instrumentation , Cochlear Implants , Hearing Loss/therapy , Hearing , Persons With Hearing Impairments/rehabilitation , Pitch Discrimination , Speech Perception , Acoustic Stimulation , Adolescent , Adult , Aged , Comprehension , Cross-Over Studies , Electric Stimulation , Female , Hearing Loss/diagnosis , Hearing Loss/physiopathology , Humans , Longitudinal Studies , Male , Middle Aged , Noise/adverse effects , Perceptual Masking , Persons With Hearing Impairments/psychology , Speech Intelligibility , Young Adult
3.
Environ Health Perspect ; 17: 55-63, 1976 Oct.
Article in English | MEDLINE | ID: mdl-1026419

ABSTRACT

An overview of commercially used flame retardants is give. The most used flame retardants are illustrated and the seven major markets, which use 96% of all flame-retarded polymers, are described. Annual flame retardant growth rate for each major market is also projected. Toxicity data are reviewed on only those compositions that are considered commercially significant today. This includes 18 compounds or families of compounds and four inherently flame-retarded polymers. Toxicological studies of flame retardants for most synthetic materials are of recent origin and only a few of the compounds have been evaluated in any great detail. Considerable toxicological problems may exist in the manufacturing of some flame retardants, their by-products, and possible decomposition products.


Subject(s)
Fires/prevention & control , Plastics/toxicity , Animals , Antimony/toxicity , Chemical Phenomena , Chemistry , Female , Humans , Hydrocarbons, Brominated/toxicity , Hydrocarbons, Chlorinated/toxicity , Male , Mice , Organophosphorus Compounds/toxicity , Polymers/toxicity , Rabbits , Rats
4.
Environ Health Perspect ; 11: 59-69, 1975 Jun.
Article in English | MEDLINE | ID: mdl-1175568

ABSTRACT

The four processes involved in the flammability of materials are described and related to the various flame retardance mechanisms that may operate. Following this the four practical approaches used in improving flame retardance of materials are described. Each approach is illustrated with a number of typical examples of flame retardants or synthetic procedures used. This overview of flammability, flame retardance, and flame retardants used is followed by a more detailed examination of most of the plastics manufactured in the United States during 1973, their consumption patterns, and the primary types of flame retardants used in the flame retardance of the most used plastics. The main types of flame retardants are illustrated with a number of typical commercial examples. Statistical data on flame retardant market size, flame retardant growth in plastics, and price ranges of common flame retardants are presented.


Subject(s)
Polymers/standards , Thermal Conductivity , Antimony , Chemical Industry , Costs and Cost Analysis , Fires/prevention & control , Halogens , Methods , Nitrogen , Oxides , Phosphorus , Plastics/standards , Polymers/chemical synthesis , Textiles/standards , United States
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