Enhancing creativity by altering the frontoparietal control network functioning using transcranial direct current stimulation.

The left angular gyrus (AG), part of the frontotemporal network, is implicated in creative thinking, including verbal creativity tasks such as novel metaphor generation. The current study tested the effects of tDCS over the left AG on two metaphor generation tasks. The study was a randomized, double-blind, sham-controlled, crossover study of anodal vs. cathodal stimulation by tDCS. Compared to sham, cathodal stimulation resulted in significantly increased novel metaphor generation, while anodal stimulation increased conventional metaphor generation. Higher motivation (behavioral approach system's "fun-seeking") was associated with greater metaphor creativity in the sham condition, and lower fun seeking was associated with producing a greater quantity of conventional metaphors. Following active stimulation, motivation traits no longer contributed to creative metaphor generation. Thus, the beneficial effect of cathodal tDCS over the left AG in generation of novel metaphors is through restraining the control network. The current study gives a glimpse into the neural basis for creative thinking.

Music-related abilities among readers with dyslexia.

Research suggests that a central difficulty in dyslexia may be impaired rapid temporal processing. Good temporal processing is also needed for musical perception, which relies on the ability to detect rapid changes. Our study is the first to measure the perception of adults with and without dyslexia on all three dimensions of music (rhythm, pitch, and spectrum), as well as their capacity for auditory imagery and detection of slow changes, while controlling for working memory. Participants were undergraduate students, aged 20-35 years: 26 readers with dyslexia and 30 typical readers. Participants completed a battery of tests measuring aptitude for recognizing the similarity/difference in tone pitch or rhythm, spectral resolution, vividness/control of auditory imagination, the ability to detect slow changes in auditory stimuli, and working memory. As expected, readers with dyslexia showed poorer performance in pitch and rhythm than controls, but outperformed them in spectral perception. The data for each test was analyzed separately while controlling for the letter-number sequencing score. No differences between groups were found in slow-change detection or auditory imagery. Our results demonstrated that rapid temporal processing appears to be the main difficulty of readers with dyslexia, who demonstrated poorer performance when stimuli were presented quickly rather than slowly and better performance on a task when no temporal component was involved. These findings underscore the need for further study of temporal processing in readers with dyslexia. Remediation of temporal processing deficits may unmask the preserved or even superior abilities of people with dyslexia, leading to enhanced ability in all areas that utilize the temporal component.

The effect of stimulus frequency, spectrum, duration, and location on temporal order judgment thresholds: distribution analysis.

The present study aimed to examine whether the judgments of temporal order are made by the same "central processor" regardless of the characteristics of the sound stimuli. The influence of stimulus parameters (e.g., frequency, spectrum, duration, location) on auditory temporal order judgment (TOJ) thresholds was tested in seven groups with a total of 192 participants received two-tone sequences of different: frequencies (3 groups); spectrum widths, via a pure tone and a Gaussian noise burst (1 group); durations (2 groups); or locations, via asynchronous presentation to each ear (1 group). No difference in the mean rankings of TOJ thresholds was found for frequency, spectrum, and location parameters. TOJ thresholds for the duration condition, however, were significantly longer than for any of the other conditions. Notably, the threshold distributions for all the parameters (frequency, spectrum, duration, location) differed in shape. These findings raise the question as to whether we can rely upon the mean or median threshold as truly representative of TOJ threshold data. Furthermore, the data suggest that temporal order judgments for the different stimulus parameters are processed differently. The differences observed when analyzing the data with central tendency measures, as compared to analyzing the threshold distributions, may explain some of the mixed results reported in the literature on the mechanisms involved in temporal processing of different parameters. Stimulus parameters influence TOJ threshold distributions and response patterns, and may provide additional cues, beyond the standard temporal cue inherent in the TOJ procedure, by which participants may judge the order of the stimuli.

Auditory temporal processing, reading, and phonological awareness among aging adults.

Auditory temporal processing (ATP) has been related in the literature to both speech perception as well as reading and phonological awareness. In aging adults, it is known to be related to difficulties in speech perception. In the present study, we aimed to test whether an age-related deficit in ATP would also be accompanied by poor reading and phonological awareness. Thirty-eight aging adults were compared to 55 readers with dyslexia and 42 young normal readers on temporal order judgment (TOJ), speech perception, reading, and phonological awareness tests. Aging adults had longer TOJ thresholds than young normal readers, but shorter than readers with dyslexia; however, they had lower speech perception accuracy than both groups. Phonological awareness of the aging adults was better than readers with dyslexia, but poorer than young normal readers, although their reading accuracy was similar to that of the young controls. This is the first report on poor phonological awareness among aging adults. Suprisingly, it was not accompanied by difficulties in reading ability, and might instead be related to aging adults' difficulties in speech perception. This newly discovered relationship between ATP and phonological awareness among aging adults appears to extend the existing understanding of this relationship, and suggests it should be explored in other groups with ATP deficits.

Improving Naming Abilities Among Healthy Young-Old Adults Using Transcranial Direct Current Stimulation.

Transcranial direct current stimulation (tDCS) is a noninvasive tool to facilitate brain plasticity and enhance language abilities. Our study aims to search for a potential beneficial influence of tDCS on a cognitive linguistic task of naming which found to decline during aging. A group of fifteen healthy old adults [Formula: see text] were tested in naming 50 pictures of objects. Each subject participated in two sessions spanning on a one week period. One session included active tDCS stimulation and the other sham-placebo like stimulation. Subjects were blinded to stimulation type. During the active stimulation a bilateral protocol of anodal tDCS to the left Inferior Frontal Gyrus (IFG) combined with cathodal tDCS to the right IFG was delivered. Half of participants received active stimulation at the first session and sham at the second and half received the stimulations at the opposite order. Naming reaction time was measured at baseline, after active tDCS stimulation and after sham. 10 min of bilateral tDCS stimulation which was given after sham (training) was found to reduce naming reaction time among healthy adult subjects. These findings support the cooperative model (Weems and Reggia in Brain Lang 89:554-568, 2004) and point on strong interhemispheric connections during naming processing. It is also demonstrate the advantage of training to intensify the therapeutic effect of tDCS. Our results pinpoint on a potential tool to facilitate naming among aging people.

The effect of being human and the basis of grammatical word order: Insights from novel communication systems and young sign languages.

This study identifies a central factor that gives rise to the different word orders found in the world's languages. In the last decade, a new window on this long-standing question has been provided by data from young sign languages and invented gesture systems. Previous work has assumed that word order in both invented gesture systems and young sign languages is driven by the need to encode the semantic/syntactic roles of the verb's arguments. Based on the responses of six groups of participants, three groups of hearing participants who invented a gestural system on the spot, and three groups of signers of relatively young sign languages, we identify a major factor in determining word order in the production of utterances in novel and young communication systems, not suggested by previous accounts, namely the salience of the arguments in terms of their human/animacy properties: human arguments are introduced before inanimate arguments ('human first'). This conclusion is based on the difference in word order patterns found between responses to depicted simple events that vary as to whether both subject and object are human or whether the subject is human and the object inanimate. We argue that these differential patterns can be accounted for uniformly by the 'human first' principle. Our analysis accounts for the prevalence of SOV order in clauses with an inanimate object in all groups (replicating results of previous separate studies of deaf signers and hearing gesturers) and the prevalence of both SOV and OSV in clauses with a human object elicited from the three groups of participants who have the least interference from another linguistic system (nonliterate deaf signers who have had little or no exposure to another language). It also provides an explanation for the basic status of SOV order suggested by other studies, as well as the scarcity of the OSV order in languages of the world, despite its appearance in novel communication systems. The broadest implication of this study is that the basic cognitive distinction between humans and inanimate entities is a crucial factor in setting the wheels of word ordering in motion.