ABSTRACT
The percentage of subjects affected by different chromosomes aberrations, does not differ in subjects occupationally exposed to radiations and in controls. On the other hand the higher percentage of aberrations in the total number of cells in radioexposed subjects is highly significant. Severe limitations employing the cariotipic investigation for insurance finalities are prospected.
Subject(s)
Chromosome Aberrations , Radiology , Adult , Aged , Environmental Exposure , Female , Humans , Karyotyping , Male , Middle Aged , Mitosis/radiation effects , Technology, Radiologic , WorkforceABSTRACT
Lymphocyte patterns were examined in patient with breast cancer. A significant difference (p=0.05) was noted between the four stages of the disease before surgery only, especially in subjects aged 60-80 yr. After surgery and also after subsequent treatment, there was a highly significant fall in levels in subjects aged 40-80 yr with 1st and 2nd stage cancers. Patients aged 60-80 yr who remained free of recurrences or metastases for 4 yr had higher lymphocyte levels (p=0.001) initially. It is therefore felt that in older patients the initial lymphocyte value is of prognostic value.