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4.
Klin Khir ; (7): 55-8, 2008 Jul.
Article in Ukrainian | MEDLINE | ID: mdl-19048824

ABSTRACT

Estrogens and liposomes positively influence current wounds healing. But a degree of their influence as separately, and in a combination with each other, on current of purulent wounds are investigated insufficiently. The purpose of research--to estimate dynamics of current of experimental purulent wounds of soft fabrics at use in complex treatment estrogens and liposomes. Modelled a purulent wound. All animals treated according to standard techniques. An animal of the first group to complex treatment added estrogens, the second--liposomes, the third--simultaneously estrogens and liposomes. Determined a level oxyproline, RNA, DNA, index RNA/DNA in wounds. Use in complex treatment of purulent wounds estrogens and liposomes leads to increase in synthesis of collagen, increase of biosynthetic activity and repair processes in the field of a wound in the second and a third phase of current wounds process which are more expressed at their combined application.


Subject(s)
Estrogens/pharmacology , Liposomes/metabolism , Surgical Wound Infection/drug therapy , Wound Healing/drug effects , Animals , Estrogens/administration & dosage , Hydroxyproline/blood , Sheep
7.
Klin Khir ; (9): 42-3, 2000 Sep.
Article in Ukrainian | MEDLINE | ID: mdl-11474612

ABSTRACT

Results of studying of the woundhealing effect of preparation vermilat for injections, which constitutes the extract of polypeptide origin, were adduced. The skin wound was done to the Wistar line rats and than the preparation in 0.1 mg dose of dry substance was injected. The preparation had caused pronounced effect on regeneration of tissues. The expediency of application of the preparation in the wound healing process during its second and third stages was proved.


Subject(s)
Peptides/pharmacology , Peptides/therapeutic use , Wound Healing/drug effects , Animals , Injections, Intramuscular , Male , Rats , Rats, Wistar
8.
Klin Khir ; (11-12): 73-4, 1997.
Article in Ukrainian | MEDLINE | ID: mdl-9615016

ABSTRACT

An acute destructive pancreatitis (ADP) was simulated according to the original method with subsequent conduction of the conventional conservative therapy and pancreatic resection in 25 mongrel dogs. The mortality due to ADP lessening was promoted by the new biologically-active substance application.


Subject(s)
Biological Products/therapeutic use , Pancreatitis, Acute Necrotizing/drug therapy , Pancreatitis, Acute Necrotizing/surgery , Animals , Dogs , Male
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