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1.
Neurosurg Clin N Am ; 11(3): 479-89, 2000 Jul.
Article in English | MEDLINE | ID: mdl-10918018

ABSTRACT

Although medical history and physical examination should lead to diagnosis of chronic subdural hematomas, 40% of these patients are likely to be misdiagnosed because many of these symptoms occur in other disease processes, such as transient ischemic attacks, stroke, dementia, and tumors. Computed tomography remains one of the most useful tools in the evaluation of these patients because of its rapidity, cost, availability, and pathologic sensitivity.


Subject(s)
Hematoma, Subdural, Chronic/diagnostic imaging , Tomography, X-Ray Computed , Diagnosis, Differential , Humans , Neurologic Examination , Sensitivity and Specificity
2.
J Neurosurg Anesthesiol ; 8(3): 199-207, 1996 Jul.
Article in English | MEDLINE | ID: mdl-8803831

ABSTRACT

Cerebral vasospasm remains the principal cause of morbidity and mortality following successful clipping of intracranial aneurysms. Current management often requires subjective judgments concerning presumed abnormalities of cerebral blood flow. In this study, a combined intracranial pressure (ICP)-laser Doppler flowmetry (LDF) fiberoptic probe that permits continuous monitoring of local cerebral blood flow (lCBF) was used in the postoperative management of 20 aneurysm patients. Using this probe, lCBF was simultaneously recorded and integrated on a real time basis with other physiological parameters, including ICP, systemic arterial pressure, pulmonary arterial pressure, central venous pressure, and pulse oximetry. The combined probe also provided the ability to obtain precise and detailed information concerning the presence or absence of cerebral autoregulation and CO2 vascular reactivity, and allowed calculation of the cerebral vascular resistance. Continuous monitoring of lCBF in this manner complemented by transcranial Doppler and angiographic data permitted early detection of cerebral ischemia, helped to differentiate cerebral ischemia from edema and hyperemia, was useful in titrating blood pressure and fluid management, provided direct feedback about the effectiveness of instituted therapies, and determined early on when medical management was of no avail and that interventional neuroradiology was indicated. Evidence is presented that the presence of angiographic vasospasm and increased velocities on TCD do not always correlate with ischemia in the microcirculation and that direct measurements of lCBF are often at variance with calculations of cerebral perfusion pressure (CPP).


Subject(s)
Cerebrovascular Circulation , Intracranial Aneurysm/physiopathology , Laser-Doppler Flowmetry/methods , Subarachnoid Hemorrhage/physiopathology , Adult , Aged , Brain Ischemia/diagnosis , Carbon Dioxide , Cerebral Angiography , Female , Homeostasis , Humans , Hypertension/drug therapy , Intracranial Aneurysm/complications , Intracranial Pressure , Male , Middle Aged , Monitoring, Physiologic , Postoperative Complications , Subarachnoid Hemorrhage/etiology , Treatment Outcome , Vascular Resistance
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