[The blood coagulation status and the immunochemical and clinical indices in patients with active rheumatism during treatment with nerobol]. / Sostoianie gemokoaguliatsii, immunobiokhimicheskie i klinicheskie pokazateli u bol'nykh aktivnym revmatizmom pri lechenii nerobolom.

Blood coagulation, immunobiochemical, and clinical characteristics were studied in patients with rheumatic fever running a protracted course treated by combined therapy including nerobol. To assess the therapeutic efficacy of nerobol, the patients were divided into 2 groups: Group 1 (30 patients) were administered combined antirheumatic therapy, Group 2 (30 patients) were administered the same + nerobol in a daily dose of 15 mg for 3-4 weeks. The findings evidence a positive effect of the drug on the status of patients in whom rheumatic fever runs a protracted course: blood procoagulative activity is reduced and anticoagulative activity elevated, blood immunobiochemical and clinical characteristics normalized.

[The importance of the complement consumption reaction for the differential diagnosis of diseases of the hepatobiliary system]. / Znachenie reaktsii potrebleniia komplementa dlia differentsial'noi diagnostiki zabolevanii gepatobiliarnoi sistemy.

A study is presented of 94 patients with chronic inflammatory diseases of the hepatobiliary system and in 22 patients with dyskinesia of the biliary tract. The importance of the complement consumption reaction was evaluated (N. I. Kondrashova modification). The results of the investigation revealed distinct increase of the level of antitissue antibodies in patients with chronic inflammatory diseases of the hepatobiliary system at the stage of exacerbation. This may be used for assessment of the activity of the pathological process, differential diagnosis of biliary tract dyskinesia and as an index of treatment efficacy.