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1.
RNA interference lowers triglyceride levels.
Lim, Gregory B.
Nat Rev Cardiol ; 2024 Jun 07.
Article in English | MEDLINE | ID: mdl-38849676
2.
No benefit of apoA-I infusion after myocardial infarction.
Lim, Gregory B.
Nat Rev Cardiol ; 21(6): 354, 2024 06.
Article in English | MEDLINE | ID: mdl-38702389

Subject(s)
Apolipoprotein A-I , Myocardial Infarction , Humans , Myocardial Infarction/drug therapy , Treatment Outcome , Infusions, Intravenous
3.
Aficamten reduces symptoms in obstructive hypertrophic cardiomyopathy.
Lim, Gregory B.
Nat Rev Cardiol ; 2024 May 28.
Article in English | MEDLINE | ID: mdl-38806635
4.
No benefit of ß-blockers after myocardial infarction with preserved ejection fraction.
Lim, Gregory B.
Nat Rev Cardiol ; 21(6): 354, 2024 06.
Article in English | MEDLINE | ID: mdl-38649758

Subject(s)
Adrenergic beta-Antagonists , Myocardial Infarction , Stroke Volume , Humans , Adrenergic beta-Antagonists/therapeutic use , Stroke Volume/drug effects , Myocardial Infarction/drug therapy , Myocardial Infarction/physiopathology , Treatment Outcome
5.
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy.
Lim, Gregory B.
Nat Rev Cardiol ; 21(6): 357, 2024 06.
Article in English | MEDLINE | ID: mdl-38654087

Subject(s)
Cardiomyopathy, Hypertrophic , Humans , Cardiomyopathy, Hypertrophic/drug therapy , Cardiomyopathy, Hypertrophic/physiopathology , Cardiomyopathy, Hypertrophic/complications , Treatment Outcome , Benzylamines , Uracil/analogs & derivatives
6.
Periodontal treatment reduces AF recurrence.
Lim, Gregory B.
Nat Rev Cardiol ; 21(6): 355, 2024 06.
Article in English | MEDLINE | ID: mdl-38664574

Subject(s)
Atrial Fibrillation , Humans , Atrial Fibrillation/therapy , Atrial Fibrillation/physiopathology , Recurrence , Periodontal Diseases/therapy , Secondary Prevention/methods , Treatment Outcome
7.
Metabolic product of excess niacin is linked to increased risk of cardiovascular events.
Lim, Gregory B.
Nat Rev Cardiol ; 21(5): 280, 2024 05.
Article in English | MEDLINE | ID: mdl-38438588

Subject(s)
Cardiovascular Diseases , Hydroxymethylglutaryl-CoA Reductase Inhibitors , Niacin , Humans , Niacin/adverse effects , Hypolipidemic Agents/adverse effects , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/chemically induced
8.
Weight loss from surgery or drug therapy reduces blood pressure.
Lim, Gregory B.
Nat Rev Cardiol ; 21(4): 218, 2024 04.
Article in English | MEDLINE | ID: mdl-38374340

Subject(s)
Hypertension , Weight Loss , Humans , Blood Pressure , Weight Loss/physiology , Obesity , Hypertension/drug therapy
9.
Fibroblast-like cells promote plaque stability in response to anti-IL-1ß therapy.
Lim, Gregory B.
Nat Rev Cardiol ; 21(3): 155, 2024 03.
Article in English | MEDLINE | ID: mdl-38263457

Subject(s)
Fibroblasts , Humans , Interleukin-1beta
10.
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors.
Lim, Gregory B.
Nat Rev Cardiol ; 21(2): 74, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38066088

Subject(s)
Heart Transplantation , Thyroxine , Humans , Thyroxine/therapeutic use , Tissue Donors , Brain Death , Brain , Dietary Supplements
11.
Aspirin exclusion in patients with an LVAD.
Lim, Gregory B.
Nat Rev Cardiol ; 21(2): 72, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38012304

Subject(s)
Heart Failure , Heart-Assist Devices , Humans , Aspirin/therapeutic use , Platelet Aggregation Inhibitors/therapeutic use , Retrospective Studies
12.
PCI for stable angina.
Lim, Gregory B.
Nat Rev Cardiol ; 21(2): 71, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38036671

Subject(s)
Angina, Stable , Percutaneous Coronary Intervention , Humans , Angina, Stable/surgery , Percutaneous Coronary Intervention/adverse effects , Quality of Life , Treatment Outcome
13.
Explaining how a cardiac reflex causes syncope.
Lim, Gregory B.
Nat Rev Cardiol ; 21(1): 9, 2024 01.
Article in English | MEDLINE | ID: mdl-37964079

Subject(s)
Heart , Syncope , Humans , Syncope/diagnosis , Syncope/etiology , Reflex
14.
Revealing the structure of the cardiac myosin filament.
Lim, Gregory B.
Nat Rev Cardiol ; 21(1): 7, 2024 01.
Article in English | MEDLINE | ID: mdl-37964080

Subject(s)
Cardiac Myosins , Myocardium , Humans , Cardiac Myosins/genetics , Cardiac Myosins/analysis , Cardiac Myosins/chemistry , Heart
15.
SARS-CoV-2 infects macrophages in coronary atherosclerotic plaques.
Lim, Gregory B.
Nat Rev Cardiol ; 20(12): 797, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37853160

Subject(s)
COVID-19 , Coronary Artery Disease , Plaque, Atherosclerotic , Humans , SARS-CoV-2 , Macrophages , Coronary Vessels
16.
No benefit of colchicine to prevent AF or myocardial injury after non-cardiac surgery.
Lim, Gregory B.
Nat Rev Cardiol ; 20(11): 719, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37666904
17.
VA-ECMO does not increase survival in MI-related cardiogenic shock.
Lim, Gregory B.
Nat Rev Cardiol ; 20(11): 720, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37674058
18.
Cholesterol catabolism and bile acid synthesis in cardiomyocytes promote inflammation and heart failure.
Lim, Gregory B.
Nat Rev Cardiol ; 20(10): 647, 2023 10.
Article in English | MEDLINE | ID: mdl-37524809

Subject(s)
Heart Failure , Myocytes, Cardiac , Humans , Myocytes, Cardiac/metabolism , Bile Acids and Salts , Cholesterol/metabolism , Inflammation
19.
Testosterone-replacement therapy does not increase cardiac events in men with hypogonadism.
Lim, Gregory B.
Nat Rev Cardiol ; 20(9): 581, 2023 09.
Article in English | MEDLINE | ID: mdl-37391471

Subject(s)
Cardiovascular Diseases , Hypogonadism , Male , Humans , Hypogonadism/drug therapy , Testosterone/adverse effects
20.
Antibody treatment to deplete transthyretin amyloid deposits in the heart.
Lim, Gregory B.
Nat Rev Cardiol ; 20(8): 513, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37286706

Subject(s)
Plaque, Amyloid , Prealbumin , Humans , Prealbumin/analysis , Amyloid , Heart
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