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1.
Am J Infect Control ; 51(3): 248-254, 2023 03.
Article in English | MEDLINE | ID: mdl-36375707

ABSTRACT

BACKGROUND: Reducing the transmission of SARS-CoV-2 from asymptomatic and pre-symptomatic patients is critical in controlling the circulation of the virus. METHODS: This study evaluated the prevalence of Reverse transcription polymerase chain reaction (RT-PCR) positivity in serial tests in 429 asymptomatic health care workers (HCW) and its impact on absenteeism. HCW from a COVID-19 reference hospital were tested, screened, and placed on leave. A time-series segmented regression of weekly absenteeism rates was used, and cases of infection among hospitalized patients were analyzed. Viral gene sequencing and phylogenetic analysis were performed on samples from HCW who had a positive result. RESULTS: A significant decrease in absenteeism was detected 3-4 weeks after the intervention at a time of increased transmission within the city. The prevalence of RT-PCR positivity among asymptomatic professionals was 17.3%. Phylogenetic analyses (59 samples) detected nine clusters, two of them strongly suggestive of intrahospital transmission with strains (75% B.1.1.28) circulating in the region during this period. CONCLUSIONS: Testing and placing asymptomatic professionals on leave contributed to control strategy for COVID-19 transmission in the hospital environment, and in reducing positivity and absenteeism, which directly influences the quality of care and exposes professionals to an extra load of stress.


Subject(s)
COVID-19 , Humans , COVID-19/diagnosis , COVID-19/epidemiology , SARS-CoV-2/genetics , COVID-19 Nucleic Acid Testing , Pandemics/prevention & control , Absenteeism , Phylogeny , Health Personnel , Hospitals , COVID-19 Testing
2.
In. Focaccia, Roberto. Tratado de hepatites virais. São Paulo, Atheneu, 2002. p.253-258.
Monography in Portuguese | LILACS, Sec. Est. Saúde SP | ID: lil-334827

Subject(s)
Humans , Pregnancy , Hepatitis C
3.
In. Veronesi, Ricardo; Focaccia, Roberto. Tratado de infectologia: v.1. Säo Paulo, Atheneu, 2 ed; 2002. p.184-189, tab. (BR).
Monography in Portuguese | LILACS | ID: lil-317664
4.
Campinas; s.n; dez. 1999. 162 p. tab, graf.
Thesis in Portuguese | LILACS | ID: lil-309978

ABSTRACT

O estudo realizado no Hospital Universitário da Pontifícia Universidade Católica de Campinas entre janeiro de 1994 e julho de 1998 constou de duas partes: a primeira, sobre a soroprevalência do VHC entre parturientes, os fatores de risco envolvidos e o potencial de infectividade entre as mulheres com anti-VHC-EIA positivo,e a segunda, sobre a transmissäo vertical do VHC. Na investigaçäo da prevalência dessa infecçäo, participaram 6995 mulheres que tiveram o sangue coletado na sal de parto e que responderam a uma entrevista padräo, realizada durante a internaçäo, objetivando a pesquisa de antecedentes epidemiológicos relativos a microosganismos veiculados pelas vias sanguíneas e (ou) sexual. Utilizaram-se análises de associaçäo e modelos de regressäo múltipla na relaçäo da positividade do RIBA e da presença do RNA-VHC com as variáveis epidemiológicas.


Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Hepatitis C , Pregnancy , Infectious Disease Transmission, Vertical , Seroepidemiologic Studies
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